DUSP15 protein (human) - STRING database

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DUSP15

Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases (235 aa)

Predicted Functional Partners:

DUSP23

0.708

XKR7

0.645

FOXS1

0.581

FAM64A

0.569

FAM222A

0.568

CCM2L

0.566

ECSCR

0.562

PPP1R32

0.556

C7orf57

0.546

RASL11A

0.538

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7orf57	DUSP15	ENSP00000335500	ENSP00000341658	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	0.546
C7orf57	FAM222A	ENSP00000335500	ENSP00000443292	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	0.660
C7orf57	PPP1R32	ENSP00000335500	ENSP00000344140	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Protein phosphatase 1 regulatory subunit 32	0.652
C7orf57	RASL11A	ENSP00000335500	ENSP00000241463	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Ras-like protein family member 11A; Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription (By similarity); Belongs to the small GTPase superfamily. Ras family	0.591
CCM2L	DUSP15	ENSP00000262659	ENSP00000341658	Cerebral cavernous malformations 2 protein-like; CCM2 like scaffolding protein	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	0.566
CCM2L	FOXS1	ENSP00000262659	ENSP00000365145	Cerebral cavernous malformations 2 protein-like; CCM2 like scaffolding protein	Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes	0.492
CCM2L	XKR7	ENSP00000262659	ENSP00000477059	Cerebral cavernous malformations 2 protein-like; CCM2 like scaffolding protein	XK-related protein 7; XK related family	0.712
DUSP15	C7orf57	ENSP00000341658	ENSP00000335500	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	0.546
DUSP15	CCM2L	ENSP00000341658	ENSP00000262659	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Cerebral cavernous malformations 2 protein-like; CCM2 like scaffolding protein	0.566
DUSP15	DUSP23	ENSP00000341658	ENSP00000357087	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Dual specificity protein phosphatase 23; Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14); Atypical dual specificity phosphatases	0.708
DUSP15	ECSCR	ENSP00000341658	ENSP00000479243	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2; Belongs to the ECSCR family	0.562
DUSP15	FAM222A	ENSP00000341658	ENSP00000443292	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	0.568
DUSP15	FAM64A	ENSP00000341658	ENSP00000250056	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Protein PIMREG; During mitosis, may play a role in the control of metaphase-to-anaphase transition	0.569
DUSP15	FOXS1	ENSP00000341658	ENSP00000365145	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes	0.581
DUSP15	PPP1R32	ENSP00000341658	ENSP00000344140	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Protein phosphatase 1 regulatory subunit 32	0.556
DUSP15	RASL11A	ENSP00000341658	ENSP00000241463	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	Ras-like protein family member 11A; Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription (By similarity); Belongs to the small GTPase superfamily. Ras family	0.538
DUSP15	XKR7	ENSP00000341658	ENSP00000477059	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	XK-related protein 7; XK related family	0.645
DUSP23	DUSP15	ENSP00000357087	ENSP00000341658	Dual specificity protein phosphatase 23; Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14); Atypical dual specificity phosphatases	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	0.708
ECSCR	DUSP15	ENSP00000479243	ENSP00000341658	Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2; Belongs to the ECSCR family	Dual specificity protein phosphatase 15; May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6; Atypical dual specificity phosphatases	0.562
ECSCR	FAM64A	ENSP00000479243	ENSP00000250056	Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2; Belongs to the ECSCR family	Protein PIMREG; During mitosis, may play a role in the control of metaphase-to-anaphase transition	0.647

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