FAM111B protein (human) - STRING database

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FAM111B

Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family (734 aa)

Predicted Functional Partners:

CAPNS1

0.680

NPPC

0.626

PUS7L

0.603

MS4A15

0.581

C7orf57

0.579

FAM222A

0.551

PPP1R32

0.543

IER5L

0.521

F2R

0.518

GRIN2B

0.517

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7orf57	FAM111B	ENSP00000335500	ENSP00000341565	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	0.579
C7orf57	FAM222A	ENSP00000335500	ENSP00000443292	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	0.660
C7orf57	PPP1R32	ENSP00000335500	ENSP00000344140	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	Protein phosphatase 1 regulatory subunit 32	0.652
CAPNS1	FAM111B	ENSP00000246533	ENSP00000341565	Calpain small subunit 1; Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; EF-hand domain containing	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	0.680
F2R	FAM111B	ENSP00000321326	ENSP00000341565	Proteinase-activated receptor 1; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development; F2R receptors	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	0.518
FAM111B	C7orf57	ENSP00000341565	ENSP00000335500	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	0.579
FAM111B	CAPNS1	ENSP00000341565	ENSP00000246533	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Calpain small subunit 1; Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; EF-hand domain containing	0.680
FAM111B	F2R	ENSP00000341565	ENSP00000321326	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Proteinase-activated receptor 1; High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development; F2R receptors	0.518
FAM111B	FAM222A	ENSP00000341565	ENSP00000443292	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	0.551
FAM111B	GRIN2B	ENSP00000341565	ENSP00000477455	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. [...]	0.517
FAM111B	IER5L	ENSP00000341565	ENSP00000361569	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Immediate early response 5 like	0.521
FAM111B	MS4A15	ENSP00000341565	ENSP00000386022	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains	0.581
FAM111B	NPPC	ENSP00000341565	ENSP00000387159	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	C-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity); Endogenous ligands	0.626
FAM111B	PPP1R32	ENSP00000341565	ENSP00000344140	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Protein phosphatase 1 regulatory subunit 32	0.543
FAM111B	PUS7L	ENSP00000341565	ENSP00000415899	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	Pseudouridylate synthase 7 like	0.603
FAM222A	C7orf57	ENSP00000443292	ENSP00000335500	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57	0.660
FAM222A	FAM111B	ENSP00000443292	ENSP00000341565	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	0.551
FAM222A	PPP1R32	ENSP00000443292	ENSP00000344140	Protein FAM222A; Family with sequence similarity 222 member A; Belongs to the FAM222 family	Protein phosphatase 1 regulatory subunit 32	0.652
GRIN2B	FAM111B	ENSP00000477455	ENSP00000341565	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. [...]	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	0.517
IER5L	FAM111B	ENSP00000361569	ENSP00000341565	Immediate early response 5 like	Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family	0.521

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