CLEC18B protein (human) - STRING database

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CLEC18B

C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing (455 aa)

Predicted Functional Partners:

SMIM34B

0.669

TMEM52B

0.568

C9orf66

0.557

TMEM72

0.523

MYL12B

0.440

RNF152

0.421

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C9orf66	CLEC18B	ENSP00000371824	ENSP00000341051	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	0.557
C9orf66	SMIM34B	ENSP00000371824	ENSP00000397039	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	annotation not available	0.668
C9orf66	TMEM52B	ENSP00000371824	ENSP00000371348	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	Transmembrane protein 52B	0.543
C9orf66	TMEM72	ENSP00000371824	ENSP00000374234	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	Transmembrane protein 72	0.475
CLEC18B	C9orf66	ENSP00000341051	ENSP00000371824	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	0.557
CLEC18B	MYL12B	ENSP00000341051	ENSP00000463559	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	0.440
CLEC18B	RNF152	ENSP00000341051	ENSP00000316628	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating ’Lys-63’-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates ’Lys-48’-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed; Ring finger proteins	0.421
CLEC18B	SMIM34B	ENSP00000341051	ENSP00000397039	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	annotation not available	0.669
CLEC18B	TMEM52B	ENSP00000341051	ENSP00000371348	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	Transmembrane protein 52B	0.568
CLEC18B	TMEM72	ENSP00000341051	ENSP00000374234	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	Transmembrane protein 72	0.523
MYL12B	CLEC18B	ENSP00000463559	ENSP00000341051	Myosin regulatory light chain 12B; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion; EF-hand domain containing	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	0.440
RNF152	CLEC18B	ENSP00000316628	ENSP00000341051	E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating ’Lys-63’-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates ’Lys-48’-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed; Ring finger proteins	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	0.421
RNF152	SMIM34B	ENSP00000316628	ENSP00000397039	E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating ’Lys-63’-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates ’Lys-48’-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed; Ring finger proteins	annotation not available	0.528
RNF152	TMEM52B	ENSP00000316628	ENSP00000371348	E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating ’Lys-63’-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates ’Lys-48’-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed; Ring finger proteins	Transmembrane protein 52B	0.499
SMIM34B	C9orf66	ENSP00000397039	ENSP00000371824	annotation not available	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	0.668
SMIM34B	CLEC18B	ENSP00000397039	ENSP00000341051	annotation not available	C-type lectin domain family 18 member B; Binds polysaccharides in a Ca(2+)-independent manner (By similarity); C-type lectin domain containing	0.669
SMIM34B	RNF152	ENSP00000397039	ENSP00000316628	annotation not available	E3 ubiquitin-protein ligase RNF152; E3 ubiquitin-protein ligase mediating ’Lys-63’-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates ’Lys-48’-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed; Ring finger proteins	0.528
SMIM34B	TMEM52B	ENSP00000397039	ENSP00000371348	annotation not available	Transmembrane protein 52B	0.669
SMIM34B	TMEM72	ENSP00000397039	ENSP00000374234	annotation not available	Transmembrane protein 72	0.589
TMEM52B	C9orf66	ENSP00000371348	ENSP00000371824	Transmembrane protein 52B	Uncharacterized protein C9orf66; Chromosome 9 open reading frame 66	0.543

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