• Version:
  • 11.0 [archived version]
STRINGSTRING
ADAL ADAL ICA1 ICA1 NXPE3 NXPE3 FAM124B FAM124B RPP38 RPP38 ASAP2 ASAP2 PKP2 PKP2 TPRG1 TPRG1 BNIPL BNIPL IGSF3 IGSF3 C9orf135 C9orf135
"TPRG1" - Tumor protein p63 regulated 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TPRG1Tumor protein p63 regulated 1; Belongs to the TPRG1 family (275 aa)    
Predicted Functional Partners:
ICA1
Islet cell autoantigen 1; May play a role in neurotransmitter secretion; Classical BAR domain containing (483 aa)
           
  0.714
FAM124B
Protein FAM124B; Family with sequence similarity 124 member B; Belongs to the FAM124 family (455 aa)
           
  0.679
PKP2
Plakophilin-2; May play a role in junctional plaques; Armadillo repeat containing (881 aa)
           
  0.668
BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein; May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death; BCH domain containing (357 aa)
           
  0.660
C9orf135
Protein C9orf135; Chromosome 9 open reading frame 135 (229 aa)
           
  0.644
ASAP2
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration; Ankyrin repeat domain containing (1006 aa)
           
  0.642
NXPE3
NXPE family member 3; Neurexophilin and PC-esterase domain family member 3 (559 aa)
           
  0.592
RPP38
Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family (283 aa)
           
  0.591
ADAL
Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) (328 aa)
           
  0.589
IGSF3
Immunoglobulin superfamily member 3; Immunoglobulin like domain containing (1214 aa)
           
  0.573
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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