node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVPR2 | C1QTNF1 | ENSP00000351805 | ENSP00000340864 | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | 0.831 |
C1QTNF1 | AVPR2 | ENSP00000340864 | ENSP00000351805 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily | 0.831 |
C1QTNF1 | CBLN3 | ENSP00000340864 | ENSP00000267406 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Cerebellin-3; May be involved in synaptic functions in the CNS | 0.726 |
C1QTNF1 | CBLN4 | ENSP00000340864 | ENSP00000064571 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Cerebellin-4; May be involved in synaptic functions in the CNS. May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity) | 0.466 |
C1QTNF1 | CSPG4 | ENSP00000340864 | ENSP00000312506 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Chondroitin sulfate proteoglycan 4; Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N- terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma c [...] | 0.529 |
C1QTNF1 | FAM132B | ENSP00000340864 | ENSP00000442304 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage- produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake; Belongs to the adipolin/erythroferrone family | 0.633 |
C1QTNF1 | FOXP2 | ENSP00000340864 | ENSP00000386200 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language; Forkhead boxes | 0.461 |
C1QTNF1 | IL1B | ENSP00000340864 | ENSP00000263341 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells | 0.476 |
C1QTNF1 | PTPRE | ENSP00000340864 | ENSP00000254667 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Receptor-type tyrosine-protein phosphatase epsilon; Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity); Protein tyrosine phosphatases, receptor type | 0.510 |
C1QTNF1 | TMEM120A | ENSP00000340864 | ENSP00000473983 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family | 0.597 |
C1QTNF1 | VSNL1 | ENSP00000340864 | ENSP00000384719 | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | Visinin-like protein 1; Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner; Belongs to the recoverin family | 0.609 |
CBLN3 | C1QTNF1 | ENSP00000267406 | ENSP00000340864 | Cerebellin-3; May be involved in synaptic functions in the CNS | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | 0.726 |
CBLN3 | CBLN4 | ENSP00000267406 | ENSP00000064571 | Cerebellin-3; May be involved in synaptic functions in the CNS | Cerebellin-4; May be involved in synaptic functions in the CNS. May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity) | 0.481 |
CBLN4 | C1QTNF1 | ENSP00000064571 | ENSP00000340864 | Cerebellin-4; May be involved in synaptic functions in the CNS. May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity) | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | 0.466 |
CBLN4 | CBLN3 | ENSP00000064571 | ENSP00000267406 | Cerebellin-4; May be involved in synaptic functions in the CNS. May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity) | Cerebellin-3; May be involved in synaptic functions in the CNS | 0.481 |
CSPG4 | C1QTNF1 | ENSP00000312506 | ENSP00000340864 | Chondroitin sulfate proteoglycan 4; Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N- terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma c [...] | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | 0.529 |
CSPG4 | VSNL1 | ENSP00000312506 | ENSP00000384719 | Chondroitin sulfate proteoglycan 4; Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N- terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma c [...] | Visinin-like protein 1; Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner; Belongs to the recoverin family | 0.464 |
FAM132B | C1QTNF1 | ENSP00000442304 | ENSP00000340864 | Erythroferrone; Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage- produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake; Belongs to the adipolin/erythroferrone family | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | 0.633 |
FOXP2 | C1QTNF1 | ENSP00000386200 | ENSP00000340864 | Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language; Forkhead boxes | Complement C1q tumor necrosis factor-related protein 1; C1q and TNF related 1 | 0.461 |
FOXP2 | VSNL1 | ENSP00000386200 | ENSP00000384719 | Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language; Forkhead boxes | Visinin-like protein 1; Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner; Belongs to the recoverin family | 0.571 |