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STRINGSTRING
TFR2 TFR2 DERA DERA SLC13A2 SLC13A2 SLC13A5 SLC13A5 SLCO1B7 SLCO1B7 SLC15A5 SLC15A5 MFSD9 MFSD9 HDDC3 HDDC3 SLC7A14 SLC7A14 SLC13A3 SLC13A3 MYO18B MYO18B
"SLC15A5" - Solute carrier family 15 member 5 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SLC15A5Solute carrier family 15 member 5; Proton oligopeptide cotransporter; Solute carriers (579 aa)    
Predicted Functional Partners:
SLC13A5
Solute carrier family 13 member 5; High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily (568 aa)
      
   
  0.925
SLC13A3
Solute carrier family 13 member 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily (602 aa)
      
   
  0.723
SLC13A2
Solute carrier family 13 member 2; Cotransport of sodium ions and dicarboxylates such as succinate and citrate; Solute carriers (641 aa)
      
   
  0.717
DERA
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation (318 aa)
            
  0.664
MYO18B
Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family (2567 aa)
            
  0.558
HDDC3
Guanosine-3’,5’-bis(diphosphate) 3’-pyrophosphohydrolase MESH1; ppGpp hydrolyzing enzyme involved in starvation response (179 aa)
            
  0.554
MFSD9
Major facilitator superfamily domain containing 9 (474 aa)
            
  0.536
TFR2
Transferrin receptor protein 2; Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation; Belongs to the peptidase M28 family. M28B subfamily (801 aa)
   
   
  0.535
SLC7A14
Probable cationic amino acid transporter; May be involved in arginine transport; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family (771 aa)
      
   
  0.528
SLCO1B7
Solute carrier organic anion transporter family member 1B7 (640 aa)
            
  0.511
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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