node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DUS2 | GFOD2 | ENSP00000455229 | ENSP00000268797 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | 0.540 |
DUS2 | LRRC29 | ENSP00000455229 | ENSP00000387318 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR | Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation | 0.562 |
DUS2 | SPRYD7 | ENSP00000455229 | ENSP00000354774 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR | SPRY domain containing 7 | 0.446 |
DUS2 | ZDHHC1 | ENSP00000455229 | ENSP00000340299 | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR | Probable palmitoyltransferase ZDHHC1; Zinc finger DHHC-type containing 1; Belongs to the DHHC palmitoyltransferase family | 0.418 |
GFOD2 | DUS2 | ENSP00000268797 | ENSP00000455229 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR | 0.540 |
GFOD2 | LRRC29 | ENSP00000268797 | ENSP00000387318 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation | 0.622 |
GFOD2 | SPRYD7 | ENSP00000268797 | ENSP00000354774 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | SPRY domain containing 7 | 0.543 |
GFOD2 | ZDHHC1 | ENSP00000268797 | ENSP00000340299 | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | Probable palmitoyltransferase ZDHHC1; Zinc finger DHHC-type containing 1; Belongs to the DHHC palmitoyltransferase family | 0.489 |
INTS10 | KLHL32 | ENSP00000381064 | ENSP00000358265 | Integrator complex subunit 10; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex | Kelch-like protein 32; Kelch like family member 32; BTB domain containing | 0.581 |
INTS10 | SPRYD7 | ENSP00000381064 | ENSP00000354774 | Integrator complex subunit 10; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex | SPRY domain containing 7 | 0.462 |
INTS10 | ZDHHC1 | ENSP00000381064 | ENSP00000340299 | Integrator complex subunit 10; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex | Probable palmitoyltransferase ZDHHC1; Zinc finger DHHC-type containing 1; Belongs to the DHHC palmitoyltransferase family | 0.428 |
KLHL32 | INTS10 | ENSP00000358265 | ENSP00000381064 | Kelch-like protein 32; Kelch like family member 32; BTB domain containing | Integrator complex subunit 10; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex | 0.581 |
KLHL32 | SPRYD7 | ENSP00000358265 | ENSP00000354774 | Kelch-like protein 32; Kelch like family member 32; BTB domain containing | SPRY domain containing 7 | 0.548 |
KLHL32 | ZDHHC1 | ENSP00000358265 | ENSP00000340299 | Kelch-like protein 32; Kelch like family member 32; BTB domain containing | Probable palmitoyltransferase ZDHHC1; Zinc finger DHHC-type containing 1; Belongs to the DHHC palmitoyltransferase family | 0.495 |
LRRC29 | DUS2 | ENSP00000387318 | ENSP00000455229 | Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR | 0.562 |
LRRC29 | GFOD2 | ENSP00000387318 | ENSP00000268797 | Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation | Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly | 0.622 |
LRRC29 | SPRYD7 | ENSP00000387318 | ENSP00000354774 | Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation | SPRY domain containing 7 | 0.563 |
LRRC29 | ZDHHC1 | ENSP00000387318 | ENSP00000340299 | Leucine-rich repeat-containing protein 29; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation | Probable palmitoyltransferase ZDHHC1; Zinc finger DHHC-type containing 1; Belongs to the DHHC palmitoyltransferase family | 0.584 |
LYPLA1 | PPT1 | ENSP00000320043 | ENSP00000394863 | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons; Belongs to the palmitoyl-protein thioesterase family | 0.838 |
LYPLA1 | ZDHHC1 | ENSP00000320043 | ENSP00000340299 | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family | Probable palmitoyltransferase ZDHHC1; Zinc finger DHHC-type containing 1; Belongs to the DHHC palmitoyltransferase family | 0.428 |