| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACAA1 | ACAA2 | ENSP00000333664 | ENSP00000285093 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | 0.843 |
| ACAA1 | ACADS | ENSP00000333664 | ENSP00000242592 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | 0.980 |
| ACAA1 | ACSM6 | ENSP00000333664 | ENSP00000340296 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | Acyl-coenzyme A synthetase ACSM6, mitochondrial; acyl-CoA synthetase medium chain family member 6 | 0.438 |
| ACAA1 | COASY | ENSP00000333664 | ENSP00000464814 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | Bifunctional coenzyme A synthase; Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation; In the central section; belongs to the eukaryotic CoaD family | 0.407 |
| ACAA1 | CRAT | ENSP00000333664 | ENSP00000315013 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | Carnitine O-acetyltransferase; Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria; Belongs to the carnitine/choline acetyltransferase family | 0.718 |
| ACAA1 | CS | ENSP00000333664 | ENSP00000342056 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | Citrate synthase, mitochondrial; Citrate synthase | 0.895 |
| ACAA1 | HADH | ENSP00000333664 | ENSP00000474560 | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family | 0.995 |
| ACAA2 | ACAA1 | ENSP00000285093 | ENSP00000333664 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | 0.843 |
| ACAA2 | ACADS | ENSP00000285093 | ENSP00000242592 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | 0.984 |
| ACAA2 | ACSM6 | ENSP00000285093 | ENSP00000340296 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | Acyl-coenzyme A synthetase ACSM6, mitochondrial; acyl-CoA synthetase medium chain family member 6 | 0.479 |
| ACAA2 | COASY | ENSP00000285093 | ENSP00000464814 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | Bifunctional coenzyme A synthase; Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation; In the central section; belongs to the eukaryotic CoaD family | 0.462 |
| ACAA2 | CRAT | ENSP00000285093 | ENSP00000315013 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | Carnitine O-acetyltransferase; Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria; Belongs to the carnitine/choline acetyltransferase family | 0.449 |
| ACAA2 | CS | ENSP00000285093 | ENSP00000342056 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | Citrate synthase, mitochondrial; Citrate synthase | 0.894 |
| ACAA2 | HADH | ENSP00000285093 | ENSP00000474560 | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family | 0.989 |
| ACADS | ACAA1 | ENSP00000242592 | ENSP00000333664 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 | 0.980 |
| ACADS | ACAA2 | ENSP00000242592 | ENSP00000285093 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | 3-ketoacyl-CoA thiolase, mitochondrial; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | 0.984 |
| ACADS | ACSM6 | ENSP00000242592 | ENSP00000340296 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | Acyl-coenzyme A synthetase ACSM6, mitochondrial; acyl-CoA synthetase medium chain family member 6 | 0.906 |
| ACADS | CRAT | ENSP00000242592 | ENSP00000315013 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | Carnitine O-acetyltransferase; Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria; Belongs to the carnitine/choline acetyltransferase family | 0.533 |
| ACADS | CS | ENSP00000242592 | ENSP00000342056 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | Citrate synthase, mitochondrial; Citrate synthase | 0.424 |
| ACADS | HADH | ENSP00000242592 | ENSP00000474560 | Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Introduces a double bond at position 2 in saturated acyl-CoA’s of short chain length, i.e. less than 6 carbon atoms; Belongs to the acyl-CoA dehydrogenase family | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family | 0.927 |
