• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF286B ZNF286B TVP23B TVP23B PABPC1L2A PABPC1L2A TRIM16L TRIM16L FBXW10 FBXW10 PABPC1L2B PABPC1L2B AQP12B AQP12B TBC1D28 TBC1D28 TBC1D29 TBC1D29 TBC1D23 TBC1D23 TBC1D25 TBC1D25
"TBC1D28" - TBC1 domain family member 28 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D28TBC1 domain family member 28 (210 aa)    
Predicted Functional Partners:
TBC1D29
TBC1 domain family member 29 (150 aa)
           
  0.734
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family (205 aa)
     
   
  0.733
PABPC1L2B
poly(A) binding protein cytoplasmic 1 like 2B; RNA binding motif containing (200 aa)
     
   
  0.689
PABPC1L2A
poly(A) binding protein cytoplasmic 1 like 2A; RNA binding motif containing (200 aa)
     
   
  0.689
TRIM16L
Tripartite motif-containing protein 16-like protein; Tripartite motif containing 16 like; Belongs to the TRIM/RBCC family (348 aa)
     
   
  0.687
ZNF286B
Putative zinc finger protein 286B; May be involved in transcriptional regulation; Zinc fingers C2H2-type (522 aa)
     
 
  0.676
FBXW10
F-box/WD repeat-containing protein 10; Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1; F-box and WD repeat domain containing (1052 aa)
     
   
  0.619
AQP12B
Aquaporin-12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily (307 aa)
           
  0.571
TBC1D23
TBC1 domain family member 23; Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but inste [...] (699 aa)
     
   
  0.504
TBC1D25
TBC1 domain family member 25; Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes (688 aa)
     
   
  0.444
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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