• Version:
  • 11.0 [archived version]
STRINGSTRING
LRRC14 LRRC14 TRIM28 TRIM28 ZNF433 ZNF433 YPEL1 YPEL1 FHAD1 FHAD1 ARGLU1 ARGLU1
"ZNF433" - Zinc finger protein 433 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF433Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (673 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.928
FHAD1
Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1 (1412 aa)
           
  0.530
YPEL1
Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Yippee like family (119 aa)
           
  0.530
LRRC14
Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily (493 aa)
           
  0.515
ARGLU1
Arginine and glutamate-rich protein 1; Required for the estrogen-dependent expression of ESR1 target genes. Can act in cooperation with MED1 (273 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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