• Version:
  • 11.0 [archived version]
STRINGSTRING
ALPK1 ALPK1 UMODL1 UMODL1 XXYLT1 XXYLT1 DOCK9 DOCK9 SNCG SNCG FAM78B FAM78B PAQR3 PAQR3 ATP5F1 ATP5F1 FAM107B FAM107B LRRC17 LRRC17 BTN2A1 BTN2A1
"FAM78B" - Protein FAM78B in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FAM78BProtein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family (261 aa)    
Predicted Functional Partners:
FAM107B
Protein FAM107B; Family with sequence similarity 107 member B (306 aa)
           
  0.632
ATP5F1
ATP synthase F(0) complex subunit B1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechani [...] (256 aa)
           
  0.544
LRRC17
Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) (441 aa)
           
  0.535
SNCG
Gamma-synuclein; Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity); Belongs to the synuclein family (127 aa)
           
  0.524
PAQR3
Progestin and adipoQ receptor family member 3; Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi; Progestin and adipoQ receptor family (311 aa)
           
  0.511
XXYLT1
Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O- linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9; Glycosyltransferase family 8 (393 aa)
           
  0.511
DOCK9
Dedicator of cytokinesis protein 9; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation; Belongs to the DOCK family (2068 aa)
     
   
  0.503
ALPK1
Alpha-protein kinase 1; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (1244 aa)
           
  0.473
BTN2A1
Butyrophilin subfamily 2 member A1; Butyrophilins (527 aa)
     
   
  0.452
UMODL1
Uromodulin like 1 (1446 aa)
           
  0.441
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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