node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALPK1 | FAM78B | ENSP00000398048 | ENSP00000339681 | Alpha-protein kinase 1; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | 0.473 |
ATP5F1 | FAM78B | ENSP00000358737 | ENSP00000339681 | ATP synthase F(0) complex subunit B1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechani [...] | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | 0.544 |
BTN2A1 | FAM78B | ENSP00000312158 | ENSP00000339681 | Butyrophilin subfamily 2 member A1; Butyrophilins | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | 0.452 |
DOCK9 | FAM78B | ENSP00000365643 | ENSP00000339681 | Dedicator of cytokinesis protein 9; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation; Belongs to the DOCK family | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | 0.503 |
FAM107B | FAM78B | ENSP00000181796 | ENSP00000339681 | Protein FAM107B; Family with sequence similarity 107 member B | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | 0.632 |
FAM107B | LRRC17 | ENSP00000181796 | ENSP00000344242 | Protein FAM107B; Family with sequence similarity 107 member B | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | 0.494 |
FAM107B | PAQR3 | ENSP00000181796 | ENSP00000421981 | Protein FAM107B; Family with sequence similarity 107 member B | Progestin and adipoQ receptor family member 3; Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi; Progestin and adipoQ receptor family | 0.465 |
FAM78B | ALPK1 | ENSP00000339681 | ENSP00000398048 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Alpha-protein kinase 1; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation | 0.473 |
FAM78B | ATP5F1 | ENSP00000339681 | ENSP00000358737 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | ATP synthase F(0) complex subunit B1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechani [...] | 0.544 |
FAM78B | BTN2A1 | ENSP00000339681 | ENSP00000312158 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Butyrophilin subfamily 2 member A1; Butyrophilins | 0.452 |
FAM78B | DOCK9 | ENSP00000339681 | ENSP00000365643 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Dedicator of cytokinesis protein 9; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation; Belongs to the DOCK family | 0.503 |
FAM78B | FAM107B | ENSP00000339681 | ENSP00000181796 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Protein FAM107B; Family with sequence similarity 107 member B | 0.632 |
FAM78B | LRRC17 | ENSP00000339681 | ENSP00000344242 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | 0.535 |
FAM78B | PAQR3 | ENSP00000339681 | ENSP00000421981 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Progestin and adipoQ receptor family member 3; Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi; Progestin and adipoQ receptor family | 0.511 |
FAM78B | SNCG | ENSP00000339681 | ENSP00000361087 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Gamma-synuclein; Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity); Belongs to the synuclein family | 0.524 |
FAM78B | UMODL1 | ENSP00000339681 | ENSP00000386126 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Uromodulin like 1 | 0.441 |
FAM78B | XXYLT1 | ENSP00000339681 | ENSP00000309640 | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O- linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9; Glycosyltransferase family 8 | 0.511 |
LRRC17 | FAM107B | ENSP00000344242 | ENSP00000181796 | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | Protein FAM107B; Family with sequence similarity 107 member B | 0.494 |
LRRC17 | FAM78B | ENSP00000344242 | ENSP00000339681 | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family | 0.535 |
PAQR3 | FAM107B | ENSP00000421981 | ENSP00000181796 | Progestin and adipoQ receptor family member 3; Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi; Progestin and adipoQ receptor family | Protein FAM107B; Family with sequence similarity 107 member B | 0.465 |