CCDC30 protein (human) - STRING database

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CCDC30

Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family (783 aa)

Predicted Functional Partners:

BRD7

0.626

WDR64

0.626

HMGXB4

0.626

ZMAT2

0.611

PBXIP1

0.602

DUS4L

0.601

KANSL1

0.554

GJC3

0.552

BCAP29

0.549

ADCK4

0.548

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCK4	CCDC30	ENSP00000315118	ENSP00000339280	Atypical kinase COQ8B, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear- does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	0.548
ADCK4	PBXIP1	ENSP00000315118	ENSP00000357448	Atypical kinase COQ8B, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear- does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration	Pre-B-cell leukemia transcription factor-interacting protein 1; Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling	0.404
ADCK4	ZMAT2	ENSP00000315118	ENSP00000274712	Atypical kinase COQ8B, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear- does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration	Zinc finger matrin-type 2; Spliceosomal B complex	0.434
BCAP29	CCDC30	ENSP00000368414	ENSP00000339280	B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	0.549
BCAP29	DUS4L	ENSP00000368414	ENSP00000265720	B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family	tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	0.925
BCAP29	ZMAT2	ENSP00000368414	ENSP00000274712	B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family	Zinc finger matrin-type 2; Spliceosomal B complex	0.433
BRD7	CCDC30	ENSP00000378181	ENSP00000339280	Bromodomain-containing protein 7; Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at ’Tyr-216’. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at ’Lys-9’ (H3K9ac). Binds to the ESR1 promoter [...]	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	0.626
BRD7	HMGXB4	ENSP00000378181	ENSP00000216106	Bromodomain-containing protein 7; Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at ’Tyr-216’. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at ’Lys-9’ (H3K9ac). Binds to the ESR1 promoter [...]	HMG domain-containing protein 4; Negatively regulates Wnt/beta-catenin signaling during development; Non-canonical high mobility group	0.680
BRD7	WDR64	ENSP00000378181	ENSP00000355510	Bromodomain-containing protein 7; Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at ’Tyr-216’. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at ’Lys-9’ (H3K9ac). Binds to the ESR1 promoter [...]	WD repeat-containing protein 64; WD repeat domain containing	0.569
CCDC30	ADCK4	ENSP00000339280	ENSP00000315118	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	Atypical kinase COQ8B, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear- does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration	0.548
CCDC30	BCAP29	ENSP00000339280	ENSP00000368414	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family	0.549
CCDC30	BRD7	ENSP00000339280	ENSP00000378181	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	Bromodomain-containing protein 7; Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at ’Tyr-216’. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at ’Lys-9’ (H3K9ac). Binds to the ESR1 promoter [...]	0.626
CCDC30	DUS4L	ENSP00000339280	ENSP00000265720	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	0.601
CCDC30	GJC3	ENSP00000339280	ENSP00000325775	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	Gap junction gamma-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Gamma-type subfamily	0.552
CCDC30	HMGXB4	ENSP00000339280	ENSP00000216106	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	HMG domain-containing protein 4; Negatively regulates Wnt/beta-catenin signaling during development; Non-canonical high mobility group	0.626
CCDC30	KANSL1	ENSP00000339280	ENSP00000262419	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription	0.554
CCDC30	PBXIP1	ENSP00000339280	ENSP00000357448	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	Pre-B-cell leukemia transcription factor-interacting protein 1; Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling	0.602
CCDC30	WDR64	ENSP00000339280	ENSP00000355510	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	WD repeat-containing protein 64; WD repeat domain containing	0.626
CCDC30	ZMAT2	ENSP00000339280	ENSP00000274712	Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family	Zinc finger matrin-type 2; Spliceosomal B complex	0.611
DUS4L	BCAP29	ENSP00000265720	ENSP00000368414	tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family	0.925

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