| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANPEP | GCLC | ENSP00000300060 | ENSP00000229416 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Glutamate-cysteine ligase catalytic subunit | 0.938 |
| ANPEP | GGT7 | ENSP00000300060 | ENSP00000338964 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Glutathione hydrolase 7; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.948 |
| ANPEP | GSS | ENSP00000300060 | ENSP00000216951 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family | 0.903 |
| ANPEP | LAP3 | ENSP00000300060 | ENSP00000226299 | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family | 0.939 |
| FAM57A | GGT7 | ENSP00000312017 | ENSP00000338964 | Protein FAM57A; Family with sequence similarity 57 member A; TLC domain containing | Glutathione hydrolase 7; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.989 |
| GAD2 | GCLC | ENSP00000365437 | ENSP00000229416 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Glutamate-cysteine ligase catalytic subunit | 0.810 |
| GAD2 | GGT7 | ENSP00000365437 | ENSP00000338964 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Glutathione hydrolase 7; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.917 |
| GAD2 | GLUD2 | ENSP00000365437 | ENSP00000327589 | Glutamate decarboxylase 2; Catalyzes the production of GABA | Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family | 0.927 |
| GAD2 | OPLAH | ENSP00000365437 | ENSP00000480476 | Glutamate decarboxylase 2; Catalyzes the production of GABA | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate | 0.802 |
| GCLC | ANPEP | ENSP00000229416 | ENSP00000300060 | Glutamate-cysteine ligase catalytic subunit | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | 0.938 |
| GCLC | GAD2 | ENSP00000229416 | ENSP00000365437 | Glutamate-cysteine ligase catalytic subunit | Glutamate decarboxylase 2; Catalyzes the production of GABA | 0.810 |
| GCLC | GGT7 | ENSP00000229416 | ENSP00000338964 | Glutamate-cysteine ligase catalytic subunit | Glutathione hydrolase 7; Cleaves glutathione conjugates; Gamma-glutamyltransferases | 0.931 |
| GCLC | GLUD2 | ENSP00000229416 | ENSP00000327589 | Glutamate-cysteine ligase catalytic subunit | Glutamate dehydrogenase 2, mitochondrial; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission; Belongs to the Glu/Leu/Phe/Val dehydrogenases family | 0.843 |
| GCLC | GPX4 | ENSP00000229416 | ENSP00000346103 | Glutamate-cysteine ligase catalytic subunit | Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death resulting from an iron-depende [...] | 0.754 |
| GCLC | GSR | ENSP00000229416 | ENSP00000221130 | Glutamate-cysteine ligase catalytic subunit | Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol | 0.899 |
| GCLC | GSS | ENSP00000229416 | ENSP00000216951 | Glutamate-cysteine ligase catalytic subunit | Glutathione synthetase; Belongs to the eukaryotic GSH synthase family | 0.986 |
| GCLC | LAP3 | ENSP00000229416 | ENSP00000226299 | Glutamate-cysteine ligase catalytic subunit | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family | 0.902 |
| GCLC | OPLAH | ENSP00000229416 | ENSP00000480476 | Glutamate-cysteine ligase catalytic subunit | 5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate | 0.910 |
| GGT7 | ANPEP | ENSP00000338964 | ENSP00000300060 | Glutathione hydrolase 7; Cleaves glutathione conjugates; Gamma-glutamyltransferases | Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases | 0.948 |
| GGT7 | FAM57A | ENSP00000338964 | ENSP00000312017 | Glutathione hydrolase 7; Cleaves glutathione conjugates; Gamma-glutamyltransferases | Protein FAM57A; Family with sequence similarity 57 member A; TLC domain containing | 0.989 |
