node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD30BL | SLC6A16 | ENSP00000386398 | ENSP00000338627 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.493 |
ASB13 | SLC6A16 | ENSP00000350331 | ENSP00000338627 | Ankyrin repeat and SOCS box protein 13; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.473 |
ASB13 | ZNF254 | ENSP00000350331 | ENSP00000349494 | Ankyrin repeat and SOCS box protein 13; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | Zinc finger protein 254; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.462 |
CELF1 | SLC6A16 | ENSP00000435926 | ENSP00000338627 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons- promotes inclusion of the smooth muscle (SM) exon bu [...] | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.506 |
CELF1 | TNNT3 | ENSP00000435926 | ENSP00000278317 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons- promotes inclusion of the smooth muscle (SM) exon bu [...] | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.419 |
METTL25 | SLC6A16 | ENSP00000248306 | ENSP00000338627 | Methyltransferase-like protein 25; Putative methyltransferase | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.453 |
SLC1A7 | SLC36A2 | ENSP00000478639 | ENSP00000334223 | Amino acid transporter; Solute carrier family 1 member 7 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity); Belongs to the amino acid/polyamine transporter 2 family | 0.829 |
SLC1A7 | SLC6A16 | ENSP00000478639 | ENSP00000338627 | Amino acid transporter; Solute carrier family 1 member 7 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.552 |
SLC25A28 | SLC6A16 | ENSP00000359526 | ENSP00000338627 | Mitoferrin-2; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.506 |
SLC33A1 | SLC6A16 | ENSP00000376587 | ENSP00000338627 | Acetyl-coenzyme A transporter 1; Probable acetyl-CoA transporter necessary for O- acetylation of gangliosides. Negatively regulates BMP signaling; Solute carriers | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.463 |
SLC36A2 | SLC1A7 | ENSP00000334223 | ENSP00000478639 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity); Belongs to the amino acid/polyamine transporter 2 family | Amino acid transporter; Solute carrier family 1 member 7 | 0.829 |
SLC36A2 | SLC6A16 | ENSP00000334223 | ENSP00000338627 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity); Belongs to the amino acid/polyamine transporter 2 family | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | 0.716 |
SLC6A16 | ANKRD30BL | ENSP00000338627 | ENSP00000386398 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Putative ankyrin repeat domain-containing protein 30B-like; Ankyrin repeat domain containing | 0.493 |
SLC6A16 | ASB13 | ENSP00000338627 | ENSP00000350331 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Ankyrin repeat and SOCS box protein 13; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Ankyrin repeat domain containing | 0.473 |
SLC6A16 | CELF1 | ENSP00000338627 | ENSP00000435926 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons- promotes inclusion of the smooth muscle (SM) exon bu [...] | 0.506 |
SLC6A16 | METTL25 | ENSP00000338627 | ENSP00000248306 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Methyltransferase-like protein 25; Putative methyltransferase | 0.453 |
SLC6A16 | SLC1A7 | ENSP00000338627 | ENSP00000478639 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Amino acid transporter; Solute carrier family 1 member 7 | 0.552 |
SLC6A16 | SLC25A28 | ENSP00000338627 | ENSP00000359526 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Mitoferrin-2; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.506 |
SLC6A16 | SLC33A1 | ENSP00000338627 | ENSP00000376587 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Acetyl-coenzyme A transporter 1; Probable acetyl-CoA transporter necessary for O- acetylation of gangliosides. Negatively regulates BMP signaling; Solute carriers | 0.463 |
SLC6A16 | SLC36A2 | ENSP00000338627 | ENSP00000334223 | Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5; Solute carrier family 6 member 16 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity); Belongs to the amino acid/polyamine transporter 2 family | 0.716 |