• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM102B FAM102B OR10H2 OR10H2 ZNF282 ZNF282 SPACA5 SPACA5 ZNF398 ZNF398 ZNF212 ZNF212 TRIM28 TRIM28 ZNF777 ZNF777 DZIP1 DZIP1 ZNF746 ZNF746 SPACA5B SPACA5B
"ZNF212" - Zinc finger protein 212 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF212Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type (495 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.927
ZNF282
Zinc finger protein 282; Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5’-TCCACCCC-3’ sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression; Belongs to the krueppel C2H2-type zinc-finger protein family (671 aa)
     
 
0.884
ZNF398
Zinc finger protein 398; Function as a transcriptional activator; Zinc fingers C2H2-type (642 aa)
       
   
0.869
ZNF746
Zinc finger protein 746; Transcription repressor that specifically binds to the 5’-TATTTT[T/G]-3’ consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death; Zinc fingers C2H2-type (645 aa)
     
 
0.847
ZNF777
Zinc finger protein 777; May be involved in transcriptional regulation; Zinc fingers C2H2-type (831 aa)
     
 
0.825
OR10H2
Olfactory receptor 10H2; Odorant receptor; Olfactory receptors, family 10 (315 aa)
           
  0.670
SPACA5B
Sperm acrosome associated 5B; Lysozymes, c-type (159 aa)
           
  0.635
SPACA5
Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family (159 aa)
           
  0.630
DZIP1
Zinc finger protein DZIP1; May participate in spermatogenesis via its interaction with DAZ. Has a role in primary cilium formation; Belongs to the DZIP C2H2-type zinc-finger protein family (867 aa)
           
  0.572
FAM102B
Protein FAM102B; Family with sequence similarity 102 member B; NT-C2 domain containing (360 aa)
           
  0.522
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]