node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DZIP1 | ZNF212 | ENSP00000257312 | ENSP00000338572 | Zinc finger protein DZIP1; May participate in spermatogenesis via its interaction with DAZ. Has a role in primary cilium formation; Belongs to the DZIP C2H2-type zinc-finger protein family | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.572 |
FAM102B | ZNF212 | ENSP00000359052 | ENSP00000338572 | Protein FAM102B; Family with sequence similarity 102 member B; NT-C2 domain containing | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.522 |
OR10H2 | ZNF212 | ENSP00000306095 | ENSP00000338572 | Olfactory receptor 10H2; Odorant receptor; Olfactory receptors, family 10 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.670 |
SPACA5 | ZNF212 | ENSP00000305847 | ENSP00000338572 | Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.630 |
SPACA5B | ZNF212 | ENSP00000304762 | ENSP00000338572 | Sperm acrosome associated 5B; Lysozymes, c-type | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.635 |
TRIM28 | ZNF212 | ENSP00000253024 | ENSP00000338572 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.927 |
TRIM28 | ZNF282 | ENSP00000253024 | ENSP00000477841 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 282; Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5’-TCCACCCC-3’ sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.947 |
TRIM28 | ZNF398 | ENSP00000253024 | ENSP00000420418 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 398; Function as a transcriptional activator; Zinc fingers C2H2-type | 0.905 |
TRIM28 | ZNF746 | ENSP00000253024 | ENSP00000395007 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 746; Transcription repressor that specifically binds to the 5’-TATTTT[T/G]-3’ consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death; Zinc fingers C2H2-type | 0.921 |
TRIM28 | ZNF777 | ENSP00000253024 | ENSP00000247930 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 777; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.918 |
ZNF212 | DZIP1 | ENSP00000338572 | ENSP00000257312 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger protein DZIP1; May participate in spermatogenesis via its interaction with DAZ. Has a role in primary cilium formation; Belongs to the DZIP C2H2-type zinc-finger protein family | 0.572 |
ZNF212 | FAM102B | ENSP00000338572 | ENSP00000359052 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein FAM102B; Family with sequence similarity 102 member B; NT-C2 domain containing | 0.522 |
ZNF212 | OR10H2 | ENSP00000338572 | ENSP00000306095 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Olfactory receptor 10H2; Odorant receptor; Olfactory receptors, family 10 | 0.670 |
ZNF212 | SPACA5 | ENSP00000338572 | ENSP00000305847 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family | 0.630 |
ZNF212 | SPACA5B | ENSP00000338572 | ENSP00000304762 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Sperm acrosome associated 5B; Lysozymes, c-type | 0.635 |
ZNF212 | TRIM28 | ENSP00000338572 | ENSP00000253024 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.927 |
ZNF212 | ZNF282 | ENSP00000338572 | ENSP00000477841 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger protein 282; Binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat. It recognizes the 5’-TCCACCCC-3’ sequence as a core motif and exerts a strong repressive effect on HTLV-I LTR-mediated expression; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.884 |
ZNF212 | ZNF398 | ENSP00000338572 | ENSP00000420418 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger protein 398; Function as a transcriptional activator; Zinc fingers C2H2-type | 0.869 |
ZNF212 | ZNF746 | ENSP00000338572 | ENSP00000395007 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger protein 746; Transcription repressor that specifically binds to the 5’-TATTTT[T/G]-3’ consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death; Zinc fingers C2H2-type | 0.847 |
ZNF212 | ZNF777 | ENSP00000338572 | ENSP00000247930 | Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger protein 777; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.825 |