node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B3GNT7 | FNDC3B | ENSP00000287590 | ENSP00000338523 | UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 7; May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues; Beta 3-glycosyltransferases | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | 0.647 |
FAM46A | FNDC3B | ENSP00000318298 | ENSP00000338523 | Putative nucleotidyltransferase FAM46A; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | 0.687 |
FAM46A | LCN12 | ENSP00000318298 | ENSP00000360696 | Putative nucleotidyltransferase FAM46A; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | 0.490 |
FAM46A | ZNF469 | ENSP00000318298 | ENSP00000402343 | Putative nucleotidyltransferase FAM46A; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family | Zinc finger protein 469; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.515 |
FNDC3B | B3GNT7 | ENSP00000338523 | ENSP00000287590 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 7; May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues; Beta 3-glycosyltransferases | 0.647 |
FNDC3B | FAM46A | ENSP00000338523 | ENSP00000318298 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Putative nucleotidyltransferase FAM46A; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family | 0.687 |
FNDC3B | LCN12 | ENSP00000338523 | ENSP00000360696 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | 0.539 |
FNDC3B | LNX1 | ENSP00000338523 | ENSP00000263925 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | E3 ubiquitin-protein ligase LNX; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65; PDZ domain containing | 0.514 |
FNDC3B | MPDZ | ENSP00000338523 | ENSP00000439807 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses | 0.540 |
FNDC3B | RAB3GAP1 | ENSP00000338523 | ENSP00000411418 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters | 0.530 |
FNDC3B | STAT3 | ENSP00000338523 | ENSP00000264657 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Acts as a regulator of inflammatory response by regulating differenti [...] | 0.585 |
FNDC3B | TMCO1 | ENSP00000338523 | ENSP00000480514 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store | 0.575 |
FNDC3B | TRIP13 | ENSP00000338523 | ENSP00000166345 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Pachytene checkpoint protein 2 homolog; Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for [...] | 0.547 |
FNDC3B | ZNF469 | ENSP00000338523 | ENSP00000402343 | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | Zinc finger protein 469; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.672 |
LCN12 | FAM46A | ENSP00000360696 | ENSP00000318298 | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | Putative nucleotidyltransferase FAM46A; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family | 0.490 |
LCN12 | FNDC3B | ENSP00000360696 | ENSP00000338523 | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | Fibronectin type III domain-containing protein 3B; May be a positive regulator of adipogenesis; Fibronectin type III domain containing | 0.539 |
LCN12 | LNX1 | ENSP00000360696 | ENSP00000263925 | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | E3 ubiquitin-protein ligase LNX; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65; PDZ domain containing | 0.446 |
LCN12 | MPDZ | ENSP00000360696 | ENSP00000439807 | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses | 0.498 |
LCN12 | RAB3GAP1 | ENSP00000360696 | ENSP00000411418 | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | Rab3 GTPase-activating protein catalytic subunit; Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters | 0.401 |
LCN12 | ZNF469 | ENSP00000360696 | ENSP00000402343 | Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity); Lipocalins | Zinc finger protein 469; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.631 |