| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DYRK4 | FKBP4 | ENSP00000441755 | ENSP00000001008 | Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily | Peptidyl-prolyl cis-trans isomerase FKBP4; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role a [...] | 0.446 |
| DYRK4 | NRIP2 | ENSP00000441755 | ENSP00000337501 | Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | 0.732 |
| DYRK4 | TSPAN11 | ENSP00000441755 | ENSP00000261177 | Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily | Tetraspanin-11; Tetraspanin 11; Tetraspanins | 0.463 |
| DYRK4 | TSPAN9 | ENSP00000441755 | ENSP00000011898 | Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily | Tetraspanin-9; Tetraspanin 9; Belongs to the tetraspanin (TM4SF) family | 0.435 |
| FKBP4 | DYRK4 | ENSP00000001008 | ENSP00000441755 | Peptidyl-prolyl cis-trans isomerase FKBP4; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role a [...] | Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily | 0.446 |
| FKBP4 | NRIP2 | ENSP00000001008 | ENSP00000337501 | Peptidyl-prolyl cis-trans isomerase FKBP4; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role a [...] | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | 0.559 |
| HERPUD2 | NRIP2 | ENSP00000379390 | ENSP00000337501 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | 0.582 |
| HERPUD2 | PPP1R12C | ENSP00000379390 | ENSP00000263433 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway | Protein phosphatase 1 regulatory subunit 12C; Regulates myosin phosphatase activity; Ankyrin repeat domain containing | 0.547 |
| NRIP2 | DYRK4 | ENSP00000337501 | ENSP00000441755 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Dual specificity tyrosine-phosphorylation-regulated kinase 4; Possible non-essential role in spermiogenesis; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily | 0.732 |
| NRIP2 | FKBP4 | ENSP00000337501 | ENSP00000001008 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Peptidyl-prolyl cis-trans isomerase FKBP4; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role a [...] | 0.559 |
| NRIP2 | HERPUD2 | ENSP00000337501 | ENSP00000379390 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway | 0.582 |
| NRIP2 | PPP1R12C | ENSP00000337501 | ENSP00000263433 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Protein phosphatase 1 regulatory subunit 12C; Regulates myosin phosphatase activity; Ankyrin repeat domain containing | 0.554 |
| NRIP2 | RORB | ENSP00000337501 | ENSP00000366093 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Nuclear receptor ROR-beta; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5’-AGGTCA-3’ preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated p [...] | 0.676 |
| NRIP2 | SF3A2 | ENSP00000337501 | ENSP00000221494 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Splicing factor 3A subunit 2; Subunit of the splicing factor SF3A required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ’E’ complex; Belongs to the SF3A2 family | 0.734 |
| NRIP2 | SUSD5 | ENSP00000337501 | ENSP00000308727 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Sushi domain containing 5 | 0.697 |
| NRIP2 | TSPAN11 | ENSP00000337501 | ENSP00000261177 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Tetraspanin-11; Tetraspanin 11; Tetraspanins | 0.569 |
| NRIP2 | TSPAN9 | ENSP00000337501 | ENSP00000011898 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Tetraspanin-9; Tetraspanin 9; Belongs to the tetraspanin (TM4SF) family | 0.555 |
| NRIP2 | XIRP1 | ENSP00000337501 | ENSP00000343140 | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | Xin actin-binding repeat-containing protein 1; Protects actin filaments from depolymerization; Belongs to the Xin family | 0.558 |
| PPP1R12C | HERPUD2 | ENSP00000263433 | ENSP00000379390 | Protein phosphatase 1 regulatory subunit 12C; Regulates myosin phosphatase activity; Ankyrin repeat domain containing | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein; Could be involved in the unfolded protein response (UPR) pathway | 0.547 |
| PPP1R12C | NRIP2 | ENSP00000263433 | ENSP00000337501 | Protein phosphatase 1 regulatory subunit 12C; Regulates myosin phosphatase activity; Ankyrin repeat domain containing | Nuclear receptor-interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 | 0.554 |
