• Version:
  • 11.0 [archived version]
STRINGSTRING
ASB2 ASB2 C1orf53 C1orf53 TRIM28 TRIM28 ZSCAN32 ZSCAN32 SCAND1 SCAND1 ZNF394 ZNF394 SCML1 SCML1 ZSCAN20 ZSCAN20 ZNF397 ZNF397 BTBD11 BTBD11 PAGE4 PAGE4
"ZNF394" - Zinc finger protein 394 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF394Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (561 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
      
    0.903
SCAND1
SCAN domain-containing protein 1; May regulate transcriptional activity; SCAN domain containing (179 aa)
        
   
0.822
ZNF397
Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor; SCAN domain containing (534 aa)
        
   
0.818
ZSCAN32
Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (697 aa)
        
   
0.812
ZSCAN20
Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Myb/SANT domain containing (1043 aa)
        
   
0.764
C1orf53
Uncharacterized protein C1orf53; Chromosome 1 open reading frame 53 (145 aa)
            
  0.538
BTBD11
Ankyrin repeat and BTB/POZ domain-containing protein BTBD11; Ankyrin repeat domain containing (1104 aa)
            
  0.498
SCML1
Sex comb on midleg-like protein 1; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. May be involved in spermatogenesis during sexual maturation (By similarity); Sterile alpha motif domain containing (329 aa)
        
 
  0.475
ASB2
Ankyrin repeat and SOCS box protein 2; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family (635 aa)
      
 
  0.412
PAGE4
PAGE family member 4 (102 aa)
            
  0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >