| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FGFR1OP2 | ZMYM2 | ENSP00000229395 | ENSP00000479904 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family | Zinc finger MYM-type protein 2; May function as a transcription factor; Zinc fingers MYM-type | 0.976 |
| FGFR1OP2 | ZNF112 | ENSP00000229395 | ENSP00000337081 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.591 |
| MANBAL | ZNF112 | ENSP00000362707 | ENSP00000337081 | Protein MANBAL; Mannosidases type beta; Belongs to the UPF0239 family | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.538 |
| RPL13 | ZNF112 | ENSP00000307889 | ENSP00000337081 | Ribosomal protein L13 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.586 |
| SH3BP4 | ZNF112 | ENSP00000386862 | ENSP00000337081 | SH3 domain-binding protein 4; May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin- mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.427 |
| TMEM123 | ZNF112 | ENSP00000381204 | ENSP00000337081 | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.545 |
| TRIM28 | ZNF112 | ENSP00000253024 | ENSP00000337081 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.942 |
| UACA | ZNF112 | ENSP00000314556 | ENSP00000337081 | Uveal autoantigen with coiled-coil domains and ankyrin repeats; Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity); Ankyrin repeat domain containing | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.420 |
| ZMYM2 | FGFR1OP2 | ENSP00000479904 | ENSP00000229395 | Zinc finger MYM-type protein 2; May function as a transcription factor; Zinc fingers MYM-type | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family | 0.976 |
| ZMYM2 | ZNF112 | ENSP00000479904 | ENSP00000337081 | Zinc finger MYM-type protein 2; May function as a transcription factor; Zinc fingers MYM-type | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.560 |
| ZNF112 | FGFR1OP2 | ENSP00000337081 | ENSP00000229395 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family | 0.591 |
| ZNF112 | MANBAL | ENSP00000337081 | ENSP00000362707 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein MANBAL; Mannosidases type beta; Belongs to the UPF0239 family | 0.538 |
| ZNF112 | RPL13 | ENSP00000337081 | ENSP00000307889 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Ribosomal protein L13 | 0.586 |
| ZNF112 | SH3BP4 | ENSP00000337081 | ENSP00000386862 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | SH3 domain-binding protein 4; May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin- mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy | 0.427 |
| ZNF112 | TMEM123 | ENSP00000337081 | ENSP00000381204 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability | 0.545 |
| ZNF112 | TRIM28 | ENSP00000337081 | ENSP00000253024 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.942 |
| ZNF112 | UACA | ENSP00000337081 | ENSP00000314556 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Uveal autoantigen with coiled-coil domains and ankyrin repeats; Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity); Ankyrin repeat domain containing | 0.420 |
| ZNF112 | ZMYM2 | ENSP00000337081 | ENSP00000479904 | Zinc finger protein 112; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Zinc finger MYM-type protein 2; May function as a transcription factor; Zinc fingers MYM-type | 0.560 |
