node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD10 | ABHD12B | ENSP00000273359 | ENSP00000336693 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Protein ABHD12B; Abhydrolase domain containing 12B | 0.603 |
ABHD10 | ABHD14A | ENSP00000273359 | ENSP00000273596 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Protein ABHD14A; Possible role in granule neuron development; Abhydrolase domain containing | 0.542 |
ABHD10 | ABHD16A | ENSP00000273359 | ENSP00000379282 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Protein ABHD16A; Abhydrolase domain containing 16A | 0.584 |
ABHD10 | ABHD16B | ENSP00000273359 | ENSP00000358932 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Protein ABHD16B; Abhydrolase domain containing 16B; Belongs to the AB hydrolase superfamily. ABHD16 family | 0.592 |
ABHD10 | ABHD3 | ENSP00000273359 | ENSP00000289119 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Phospholipase ABHD3; Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain- containing and oxidatively truncated phospholipids; Abhydrolase domain containing | 0.602 |
ABHD10 | ABHD4 | ENSP00000273359 | ENSP00000414558 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Protein ABHD4; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethan [...] | 0.416 |
ABHD10 | ABHD6 | ENSP00000273359 | ENSP00000420315 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Monoacylglycerol lipase ABHD6; Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. May also have a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity); Belongs to the AB hydrolase superfamily | 0.420 |
ABHD10 | TEX30 | ENSP00000273359 | ENSP00000365200 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Testis-expressed protein 30; Testis expressed 30 | 0.557 |
ABHD12B | ABHD10 | ENSP00000336693 | ENSP00000273359 | Protein ABHD12B; Abhydrolase domain containing 12B | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | 0.603 |
ABHD12B | ABHD14A | ENSP00000336693 | ENSP00000273596 | Protein ABHD12B; Abhydrolase domain containing 12B | Protein ABHD14A; Possible role in granule neuron development; Abhydrolase domain containing | 0.587 |
ABHD12B | ABHD16A | ENSP00000336693 | ENSP00000379282 | Protein ABHD12B; Abhydrolase domain containing 12B | Protein ABHD16A; Abhydrolase domain containing 16A | 0.587 |
ABHD12B | ABHD16B | ENSP00000336693 | ENSP00000358932 | Protein ABHD12B; Abhydrolase domain containing 12B | Protein ABHD16B; Abhydrolase domain containing 16B; Belongs to the AB hydrolase superfamily. ABHD16 family | 0.609 |
ABHD12B | ABHD3 | ENSP00000336693 | ENSP00000289119 | Protein ABHD12B; Abhydrolase domain containing 12B | Phospholipase ABHD3; Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain- containing and oxidatively truncated phospholipids; Abhydrolase domain containing | 0.626 |
ABHD12B | ABHD4 | ENSP00000336693 | ENSP00000414558 | Protein ABHD12B; Abhydrolase domain containing 12B | Protein ABHD4; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethan [...] | 0.605 |
ABHD12B | ABHD6 | ENSP00000336693 | ENSP00000420315 | Protein ABHD12B; Abhydrolase domain containing 12B | Monoacylglycerol lipase ABHD6; Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. May also have a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity); Belongs to the AB hydrolase superfamily | 0.704 |
ABHD12B | CD58 | ENSP00000336693 | ENSP00000358501 | Protein ABHD12B; Abhydrolase domain containing 12B | Lymphocyte function-associated antigen 3; Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells | 0.689 |
ABHD12B | MTPN | ENSP00000336693 | ENSP00000376800 | Protein ABHD12B; Abhydrolase domain containing 12B | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy; Belongs to the myotrophin family | 0.654 |
ABHD12B | TEX30 | ENSP00000336693 | ENSP00000365200 | Protein ABHD12B; Abhydrolase domain containing 12B | Testis-expressed protein 30; Testis expressed 30 | 0.593 |
ABHD14A | ABHD10 | ENSP00000273596 | ENSP00000273359 | Protein ABHD14A; Possible role in granule neuron development; Abhydrolase domain containing | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | 0.542 |
ABHD14A | ABHD12B | ENSP00000273596 | ENSP00000336693 | Protein ABHD14A; Possible role in granule neuron development; Abhydrolase domain containing | Protein ABHD12B; Abhydrolase domain containing 12B | 0.587 |