LRRC71 protein (human) - STRING database

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LRRC71

Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71 (559 aa)

Predicted Functional Partners:

ETV3L

0.793

PEAR1

0.747

KNDC1

0.641

KIAA0513

0.582

ARHGEF11

0.563

PCDHGA4

0.558

INSRR

0.539

ETV3

0.537

XKR4

0.520

NKPD1

0.477

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF11	ETV3L	ENSP00000357177	ENSP00000430271	Rho guanine nucleotide exchange factor 11; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth; PDZ domain containing	ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family	0.581
ARHGEF11	LRRC71	ENSP00000357177	ENSP00000336661	Rho guanine nucleotide exchange factor 11; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth; PDZ domain containing	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	0.563
ARHGEF11	PEAR1	ENSP00000357177	ENSP00000344465	Rho guanine nucleotide exchange factor 11; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth; PDZ domain containing	Platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells; Belongs to the MEGF family	0.573
ETV3	LRRC71	ENSP00000357175	ENSP00000336661	ETS translocation variant 3; Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity; ETS transcription factor family	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	0.537
ETV3L	ARHGEF11	ENSP00000430271	ENSP00000357177	ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family	Rho guanine nucleotide exchange factor 11; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth; PDZ domain containing	0.581
ETV3L	INSRR	ENSP00000430271	ENSP00000357178	ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family	Insulin receptor-related protein; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB	0.480
ETV3L	LRRC71	ENSP00000430271	ENSP00000336661	ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	0.793
ETV3L	PEAR1	ENSP00000430271	ENSP00000344465	ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family	Platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells; Belongs to the MEGF family	0.660
INSRR	ETV3L	ENSP00000357178	ENSP00000430271	Insulin receptor-related protein; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB	ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family	0.480
INSRR	LRRC71	ENSP00000357178	ENSP00000336661	Insulin receptor-related protein; Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	0.539
KIAA0513	KNDC1	ENSP00000457408	ENSP00000304437	Uncharacterized protein KIAA0513; KIAA0513	Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence	0.495
KIAA0513	LRRC71	ENSP00000457408	ENSP00000336661	Uncharacterized protein KIAA0513; KIAA0513	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	0.582
KIAA0513	NKPD1	ENSP00000457408	ENSP00000321976	Uncharacterized protein KIAA0513; KIAA0513	NTPase KAP family P-loop domain containing 1	0.440
KIAA0513	PCDHGA4	ENSP00000457408	ENSP00000458570	Uncharacterized protein KIAA0513; KIAA0513	Protocadherin gamma-A4; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.526
KIAA0513	XKR4	ENSP00000457408	ENSP00000328326	Uncharacterized protein KIAA0513; KIAA0513	XK-related protein 4; XK related family	0.459
KNDC1	KIAA0513	ENSP00000304437	ENSP00000457408	Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence	Uncharacterized protein KIAA0513; KIAA0513	0.495
KNDC1	LRRC71	ENSP00000304437	ENSP00000336661	Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	0.641
KNDC1	PCDHGA4	ENSP00000304437	ENSP00000458570	Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence	Protocadherin gamma-A4; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.436
LRRC71	ARHGEF11	ENSP00000336661	ENSP00000357177	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	Rho guanine nucleotide exchange factor 11; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth; PDZ domain containing	0.563
LRRC71	ETV3	ENSP00000336661	ENSP00000357175	Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71	ETS translocation variant 3; Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity; ETS transcription factor family	0.537

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