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  • 11.0 [archived version]
STRINGSTRING
CAMTA2 CAMTA2 PSME3 PSME3 ZNRF2 ZNRF2 FAM192A FAM192A EAF1 EAF1 RAB40AL RAB40AL RSPRY1 RSPRY1 METTL6 METTL6 ARL2BP ARL2BP EFCAB1 EFCAB1 SNX20 SNX20
"FAM192A" - Protein FAM192A in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FAM192AProtein FAM192A; Family with sequence similarity 192 member A (254 aa)    
Predicted Functional Partners:
PSME3
Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (267 aa)
       
 
  0.889
CAMTA2
Calmodulin-binding transcription activator 2; Transcription activator. May act as tumor suppressor; Belongs to the CAMTA family (1241 aa)
       
      0.864
RSPRY1
Ring finger and SPRY domain containing 1 (576 aa)
           
  0.829
EFCAB1
EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 (211 aa)
           
  0.800
RAB40AL
Ras-related protein Rab-40A-like; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the small GTPase superfamily. Rab family (278 aa)
       
      0.787
METTL6
Methyltransferase-like protein 6; Probable methyltransferase (284 aa)
     
   
  0.779
SNX20
Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion (316 aa)
           
  0.768
EAF1
ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family (268 aa)
           
  0.768
ARL2BP
ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (163 aa)
     
   
  0.764
ZNRF2
E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Ring finger proteins (242 aa)
           
  0.760
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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