node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARL2BP | EAF1 | ENSP00000219204 | ENSP00000380054 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | 0.748 |
ARL2BP | EFCAB1 | ENSP00000219204 | ENSP00000262103 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 | 0.761 |
ARL2BP | FAM192A | ENSP00000219204 | ENSP00000335808 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | Protein FAM192A; Family with sequence similarity 192 member A | 0.764 |
ARL2BP | METTL6 | ENSP00000219204 | ENSP00000407613 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | Methyltransferase-like protein 6; Probable methyltransferase | 0.713 |
ARL2BP | RSPRY1 | ENSP00000219204 | ENSP00000443176 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | Ring finger and SPRY domain containing 1 | 0.756 |
ARL2BP | SNX20 | ENSP00000219204 | ENSP00000332062 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion | 0.706 |
ARL2BP | ZNRF2 | ENSP00000219204 | ENSP00000323879 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Ring finger proteins | 0.701 |
CAMTA2 | FAM192A | ENSP00000412886 | ENSP00000335808 | Calmodulin-binding transcription activator 2; Transcription activator. May act as tumor suppressor; Belongs to the CAMTA family | Protein FAM192A; Family with sequence similarity 192 member A | 0.864 |
CAMTA2 | PSME3 | ENSP00000412886 | ENSP00000293362 | Calmodulin-binding transcription activator 2; Transcription activator. May act as tumor suppressor; Belongs to the CAMTA family | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] | 0.664 |
EAF1 | ARL2BP | ENSP00000380054 | ENSP00000219204 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | 0.748 |
EAF1 | EFCAB1 | ENSP00000380054 | ENSP00000262103 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 | 0.789 |
EAF1 | FAM192A | ENSP00000380054 | ENSP00000335808 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | Protein FAM192A; Family with sequence similarity 192 member A | 0.768 |
EAF1 | METTL6 | ENSP00000380054 | ENSP00000407613 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | Methyltransferase-like protein 6; Probable methyltransferase | 0.825 |
EAF1 | RSPRY1 | ENSP00000380054 | ENSP00000443176 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | Ring finger and SPRY domain containing 1 | 0.790 |
EAF1 | SNX20 | ENSP00000380054 | ENSP00000332062 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion | 0.748 |
EAF1 | ZNRF2 | ENSP00000380054 | ENSP00000323879 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates; Ring finger proteins | 0.747 |
EFCAB1 | ARL2BP | ENSP00000262103 | ENSP00000219204 | EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 | 0.761 |
EFCAB1 | EAF1 | ENSP00000262103 | ENSP00000380054 | EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family | 0.789 |
EFCAB1 | FAM192A | ENSP00000262103 | ENSP00000335808 | EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 | Protein FAM192A; Family with sequence similarity 192 member A | 0.800 |
EFCAB1 | METTL6 | ENSP00000262103 | ENSP00000407613 | EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 | Methyltransferase-like protein 6; Probable methyltransferase | 0.791 |