• Version:
  • 11.0 [archived version]
STRINGSTRING
GLYAT GLYAT ENSG00000273748 ENSG00000273748 SPEG SPEG OBSCN OBSCN SLC35A5 SLC35A5 SPATA21 SPATA21 ASPM ASPM MYH10 MYH10 JADE3 JADE3 OR1L3 OR1L3 PPCS PPCS
"SPATA21" - Spermatogenesis-associated protein 21 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SPATA21Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids; EF-hand domain containing (469 aa)    
Predicted Functional Partners:
OR1L3
Olfactory receptor 1L3; Odorant receptor; Olfactory receptors, family 1 (324 aa)
           
  0.669
MYH10
Myosin-10; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family (2007 aa)
       
 
  0.634
OBSCN
Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; Fibronectin type III domain containing (8923 aa)
       
 
  0.601
SPEG
Striated muscle preferentially expressed protein kinase; Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; I-set domain containing (3267 aa)
       
 
  0.601
SLC35A5
Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 (424 aa)
     
   
  0.557
JADE3
Protein Jade-3; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo; PHD finger proteins (823 aa)
           
  0.530
ASPM
Abnormal spindle-like microcephaly-associated protein; Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex [...] (3477 aa)
       
 
  0.461
GLYAT
Glycine N-acyltransferase; Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid (296 aa)
           
  0.446
PPCS
Phosphopantothenate--cysteine ligase; Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4’- phosphopantothenate to form 4-phosphopantothenoylcysteine; Belongs to the PPC synthetase family (311 aa)
       
 
  0.431
ENSG00000273748
annotation not available (123 aa)
           
  0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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