• Version:
  • 11.0 [archived version]
STRINGSTRING
CCDC47 CCDC47 TUBB TUBB KIAA1211L KIAA1211L TTC5 TTC5 TUBB2B TUBB2B TCP11L1 TCP11L1 CRLF3 CRLF3 ENSG00000258947 ENSG00000258947 QSER1 QSER1 CCDC73 CCDC73 DEPDC7 DEPDC7
"TCP11L1" - T-complex protein 11-like protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCP11L1T-complex protein 11-like protein 1; T-complex 11 like 1 (509 aa)    
Predicted Functional Partners:
TTC5
Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity); Tetratricopeptide repeat domain containing (440 aa)
       
      0.864
TUBB
Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Tubulins (444 aa)
       
      0.839
TUBB2B
Tubulin beta-2B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Plays a critical role in proper axon guidance in both central and peripheral axon tracts. Implicated in neuronal migration; Tubulins (445 aa)
       
      0.831
KIAA1211L
Uncharacterized protein KIAA1211-like; KIAA1211 like (962 aa)
           
  0.750
CCDC47
Coiled-coil domain containing 47 (483 aa)
           
  0.750
CRLF3
Cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression; Fibronectin type III domain containing (442 aa)
           
  0.747
QSER1
Glutamine and serine rich 1 (1735 aa)
     
   
  0.739
ENSG00000258947
Tubulin beta-3 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance; Belongs to the tubulin family (450 aa)
       
      0.714
CCDC73
Coiled-coil domain containing 73 (1079 aa)
           
  0.704
DEPDC7
DEP domain containing 7; Belongs to the DEPDC7 family (511 aa)
     
   
  0.661
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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