• Version:
  • 11.0 [archived version]
STRINGSTRING
NANOGNB NANOGNB ANHX ANHX VENTX VENTX DUXA DUXA KLF17 KLF17 ARGFX ARGFX RHOXF2B RHOXF2B TPRX1 TPRX1 FOXR1 FOXR1 PEPD PEPD LBX1 LBX1
"ARGFX" - Arginine-fifty homeobox in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARGFXArginine-fifty homeobox; Putative transcription factor; PRD class homeoboxes and pseudogenes (315 aa)    
Predicted Functional Partners:
DUXA
Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes (204 aa)
        
 
  0.797
TPRX1
Tetra-peptide repeat homeobox protein 1; PRD class homeoboxes and pseudogenes (411 aa)
            
  0.793
VENTX
Homeobox protein VENTX; May be involved in ventralization; NKL subclass homeoboxes and pseudogenes (258 aa)
            
  0.743
LBX1
Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes (281 aa)
            
  0.674
RHOXF2B
Rhox homeobox family member 2B; Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis; Belongs to the paired-like homeobox family. PEPP subfamily (288 aa)
        
 
  0.671
NANOGNB
NANOG neighbor homeobox (188 aa)
            
  0.669
PEPD
Xaa-Pro dipeptidase; Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen; Belongs to the peptidase M24B family. Eukaryotic-type prolidase subfamily (493 aa)
            
  0.643
KLF17
Krueppel-like factor 17; Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5’-CACCC-3’ sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity); Kruppel like factors (389 aa)
        
 
  0.612
FOXR1
Forkhead box R1 (292 aa)
      
   
  0.562
ANHX
Anomalous homeobox (379 aa)
      
 
  0.556
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >