Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EMID1 | MCF2L | ENSP00000335481 | ENSP00000440374 | EMI domain containing 1 | Guanine nucleotide exchange factor DBS; Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42; Pleckstrin homology domain containing | 0.549 |
EMID1 | MRPL45 | ENSP00000335481 | ENSP00000484903 | EMI domain containing 1 | Mitochondrial ribosomal protein L45 | 0.574 |
EMID1 | NECAB3 | ENSP00000335481 | ENSP00000246190 | EMI domain containing 1 | N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid- beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3; EF-hand domain containing | 0.560 |
EMID1 | RMND5A | ENSP00000335481 | ENSP00000283632 | EMI domain containing 1 | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | 0.575 |
EMID1 | SERPINH1 | ENSP00000335481 | ENSP00000434412 | EMI domain containing 1 | Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen; Serpin peptidase inhibitors | 0.800 |
EMID1 | SERTAD1 | ENSP00000335481 | ENSP00000350633 | EMI domain containing 1 | SERTA domain-containing protein 1; Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A | 0.539 |
EMID1 | SERTAD3 | ENSP00000335481 | ENSP00000325414 | EMI domain containing 1 | SERTA domain-containing protein 3; Strong transcriptional coactivator | 0.595 |
EMID1 | UBE2QL1 | ENSP00000335481 | ENSP00000382713 | EMI domain containing 1 | Ubiquitin-conjugating enzyme E2Q-like protein 1; Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7; Belongs to the ubiquitin-conjugating enzyme family | 0.712 |
EMID1 | USP43 | ENSP00000335481 | ENSP00000285199 | EMI domain containing 1 | Ubiquitin carboxyl-terminal hydrolase 43; May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity); Belongs to the peptidase C19 family | 0.558 |
EMID1 | ZNF611 | ENSP00000335481 | ENSP00000437616 | EMI domain containing 1 | Zinc finger protein 611; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.511 |
MCF2L | EMID1 | ENSP00000440374 | ENSP00000335481 | Guanine nucleotide exchange factor DBS; Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42; Pleckstrin homology domain containing | EMI domain containing 1 | 0.549 |
MCF2L | ZNF611 | ENSP00000440374 | ENSP00000437616 | Guanine nucleotide exchange factor DBS; Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42; Pleckstrin homology domain containing | Zinc finger protein 611; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.422 |
MRPL45 | EMID1 | ENSP00000484903 | ENSP00000335481 | Mitochondrial ribosomal protein L45 | EMI domain containing 1 | 0.574 |
MRPL45 | RMND5A | ENSP00000484903 | ENSP00000283632 | Mitochondrial ribosomal protein L45 | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | 0.553 |
MRPL45 | SERTAD1 | ENSP00000484903 | ENSP00000350633 | Mitochondrial ribosomal protein L45 | SERTA domain-containing protein 1; Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A | 0.525 |
MRPL45 | SERTAD3 | ENSP00000484903 | ENSP00000325414 | Mitochondrial ribosomal protein L45 | SERTA domain-containing protein 3; Strong transcriptional coactivator | 0.576 |
NECAB3 | EMID1 | ENSP00000246190 | ENSP00000335481 | N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid- beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3; EF-hand domain containing | EMI domain containing 1 | 0.560 |
NECAB3 | USP43 | ENSP00000246190 | ENSP00000285199 | N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid- beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3; EF-hand domain containing | Ubiquitin carboxyl-terminal hydrolase 43; May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity); Belongs to the peptidase C19 family | 0.644 |
RMND5A | EMID1 | ENSP00000283632 | ENSP00000335481 | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | EMI domain containing 1 | 0.575 |
RMND5A | MRPL45 | ENSP00000283632 | ENSP00000484903 | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | Mitochondrial ribosomal protein L45 | 0.553 |
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