GPR144 protein (human) - STRING database

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GPR144

Adhesion G-protein coupled receptor D2; Orphan receptor (972 aa)

Predicted Functional Partners:

GPR123

0.705

GPR174

0.687

GPR157

0.649

GPR173

0.596

GPR176

0.596

GPR125

0.594

PIP5K1A

0.538

ZNF800

0.511

PIP5K1C

0.485

PSMB7

0.485

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR123	GPR144	ENSP00000376384	ENSP00000335156	Adhesion G protein-coupled receptor A1; Orphan receptor	Adhesion G-protein coupled receptor D2; Orphan receptor	0.705
GPR125	GPR144	ENSP00000334952	ENSP00000335156	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Adhesion G-protein coupled receptor D2; Orphan receptor	0.594
GPR144	GPR123	ENSP00000335156	ENSP00000376384	Adhesion G-protein coupled receptor D2; Orphan receptor	Adhesion G protein-coupled receptor A1; Orphan receptor	0.705
GPR144	GPR125	ENSP00000335156	ENSP00000334952	Adhesion G-protein coupled receptor D2; Orphan receptor	Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	0.594
GPR144	GPR157	ENSP00000335156	ENSP00000366628	Adhesion G-protein coupled receptor D2; Orphan receptor	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.649
GPR144	GPR173	ENSP00000335156	ENSP00000331600	Adhesion G-protein coupled receptor D2; Orphan receptor	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	0.596
GPR144	GPR174	ENSP00000335156	ENSP00000276077	Adhesion G-protein coupled receptor D2; Orphan receptor	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	0.687
GPR144	GPR176	ENSP00000335156	ENSP00000453076	Adhesion G-protein coupled receptor D2; Orphan receptor	G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production	0.596
GPR144	PIP5K1A	ENSP00000335156	ENSP00000357883	Adhesion G-protein coupled receptor D2; Orphan receptor	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as actin cytoskeleton organiz [...]	0.538
GPR144	PIP5K1C	ENSP00000335156	ENSP00000466363	Adhesion G-protein coupled receptor D2; Orphan receptor	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as vesicle mediated transport [...]	0.485
GPR144	PSMB7	ENSP00000335156	ENSP00000259457	Adhesion G-protein coupled receptor D2; Orphan receptor	Proteasome subunit beta type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing prot [...]	0.485
GPR144	ZNF800	ENSP00000335156	ENSP00000376989	Adhesion G-protein coupled receptor D2; Orphan receptor	Zinc finger protein 800; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.511
GPR157	GPR144	ENSP00000366628	ENSP00000335156	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Adhesion G-protein coupled receptor D2; Orphan receptor	0.649
GPR157	GPR173	ENSP00000366628	ENSP00000331600	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	0.511
GPR157	GPR174	ENSP00000366628	ENSP00000276077	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	0.595
GPR173	GPR144	ENSP00000331600	ENSP00000335156	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Adhesion G-protein coupled receptor D2; Orphan receptor	0.596
GPR173	GPR157	ENSP00000331600	ENSP00000366628	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.511
GPR173	GPR174	ENSP00000331600	ENSP00000276077	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	0.575
GPR173	GPR176	ENSP00000331600	ENSP00000453076	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production	0.538
GPR174	GPR144	ENSP00000276077	ENSP00000335156	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	Adhesion G-protein coupled receptor D2; Orphan receptor	0.687

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