• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF474 ZNF474 ZBTB25 ZBTB25 TRIM28 TRIM28 ZNF555 ZNF555 ADARB2 ADARB2 C8orf48 C8orf48 FRG2 FRG2
"ZNF555" - Zinc finger protein 555 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
ZNF555Zinc finger protein 555; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (628 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.934
C8orf48
Uncharacterized protein C8orf48; Chromosome 8 open reading frame 48 (319 aa)
           
  0.626
ZBTB25
Zinc finger and BTB domain-containing protein 25; May be involved in transcriptional regulation; BTB domain containing (435 aa)
           
  0.528
ZNF474
Zinc finger protein 474; Zinc fingers C2H2-type (364 aa)
           
  0.479
FRG2
Protein FRG2; FSHD region gene 2 (279 aa)
           
  0.420
ADARB2
Double-stranded RNA-specific editase B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA; Adenosine deaminases acting on RNA (739 aa)
           
  0.412
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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