node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTC1 | EEF1A1 | ENSP00000290378 | ENSP00000339063 | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily | 0.622 |
ACTC1 | FAM65B | ENSP00000290378 | ENSP00000482957 | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maint [...] | 0.573 |
ACTC1 | IGFN1 | ENSP00000290378 | ENSP00000334714 | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | Immunoglobulin-like and fibronectin type III domain containing 1 | 0.587 |
ACTC1 | MSS51 | ENSP00000290378 | ENSP00000299432 | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | Putative protein MSS51 homolog, mitochondrial; MSS51 mitochondrial translational activator; Zinc fingers MYND-type | 0.580 |
CALML5 | IGFN1 | ENSP00000369689 | ENSP00000334714 | Calmodulin-like protein 5; Binds calcium. May be involved in terminal differentiation of keratinocytes; EF-hand domain containing | Immunoglobulin-like and fibronectin type III domain containing 1 | 0.659 |
DLK2 | IGFN1 | ENSP00000349893 | ENSP00000334714 | Protein delta homolog 2; Regulates adipogenesis | Immunoglobulin-like and fibronectin type III domain containing 1 | 0.481 |
DLK2 | NKAIN1 | ENSP00000349893 | ENSP00000362841 | Protein delta homolog 2; Regulates adipogenesis | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | 0.490 |
EEF1A1 | ACTC1 | ENSP00000339063 | ENSP00000290378 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | 0.622 |
EEF1A1 | IGFN1 | ENSP00000339063 | ENSP00000334714 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily | Immunoglobulin-like and fibronectin type III domain containing 1 | 0.580 |
FAM65B | ACTC1 | ENSP00000482957 | ENSP00000290378 | Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maint [...] | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | 0.573 |
FAM65B | IGFN1 | ENSP00000482957 | ENSP00000334714 | Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maint [...] | Immunoglobulin-like and fibronectin type III domain containing 1 | 0.665 |
FAM65B | MSS51 | ENSP00000482957 | ENSP00000299432 | Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maint [...] | Putative protein MSS51 homolog, mitochondrial; MSS51 mitochondrial translational activator; Zinc fingers MYND-type | 0.654 |
IGFN1 | ACTC1 | ENSP00000334714 | ENSP00000290378 | Immunoglobulin-like and fibronectin type III domain containing 1 | Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family | 0.587 |
IGFN1 | CALML5 | ENSP00000334714 | ENSP00000369689 | Immunoglobulin-like and fibronectin type III domain containing 1 | Calmodulin-like protein 5; Binds calcium. May be involved in terminal differentiation of keratinocytes; EF-hand domain containing | 0.659 |
IGFN1 | DLK2 | ENSP00000334714 | ENSP00000349893 | Immunoglobulin-like and fibronectin type III domain containing 1 | Protein delta homolog 2; Regulates adipogenesis | 0.481 |
IGFN1 | EEF1A1 | ENSP00000334714 | ENSP00000339063 | Immunoglobulin-like and fibronectin type III domain containing 1 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily | 0.580 |
IGFN1 | FAM65B | ENSP00000334714 | ENSP00000482957 | Immunoglobulin-like and fibronectin type III domain containing 1 | Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maint [...] | 0.665 |
IGFN1 | KLHL34 | ENSP00000334714 | ENSP00000368813 | Immunoglobulin-like and fibronectin type III domain containing 1 | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | 0.507 |
IGFN1 | MSS51 | ENSP00000334714 | ENSP00000299432 | Immunoglobulin-like and fibronectin type III domain containing 1 | Putative protein MSS51 homolog, mitochondrial; MSS51 mitochondrial translational activator; Zinc fingers MYND-type | 0.678 |
IGFN1 | NKAIN1 | ENSP00000334714 | ENSP00000362841 | Immunoglobulin-like and fibronectin type III domain containing 1 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 | 0.491 |