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  • 11.0 [archived version]
STRINGSTRING
ZC2HC1C ZC2HC1C TRIM63 TRIM63 KLHL34 KLHL34 CALML5 CALML5 MSS51 MSS51 IGFN1 IGFN1 FAM65B FAM65B ACTC1 ACTC1 NKAIN1 NKAIN1 EEF1A1 EEF1A1 DLK2 DLK2
"IGFN1" - Immunoglobulin-like and fibronectin type III domain containing 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
IGFN1Immunoglobulin-like and fibronectin type III domain containing 1 (3708 aa)    
Predicted Functional Partners:
MSS51
Putative protein MSS51 homolog, mitochondrial; MSS51 mitochondrial translational activator; Zinc fingers MYND-type (460 aa)
     
   
  0.678
FAM65B
Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maint [...] (1068 aa)
           
  0.665
CALML5
Calmodulin-like protein 5; Binds calcium. May be involved in terminal differentiation of keratinocytes; EF-hand domain containing (146 aa)
       
 
  0.659
ACTC1
Actin, alpha cardiac muscle 1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family (377 aa)
     
 
  0.587
EEF1A1
Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily (462 aa)
     
 
  0.580
KLHL34
Kelch-like protein 34; Kelch like family member 34; BTB domain containing (644 aa)
     
 
  0.507
NKAIN1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1 (207 aa)
           
  0.491
DLK2
Protein delta homolog 2; Regulates adipogenesis (383 aa)
           
  0.481
TRIM63
E3 ubiquitin-protein ligase TRIM63; E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti- [...] (353 aa)
     
 
  0.474
ZC2HC1C
Zinc finger C2HC-type containing 1C; Belongs to the ZC2HC1 family (456 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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