node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRBK2 | MYO18B | ENSP00000317578 | ENSP00000334563 | Beta-adrenergic receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.901 |
ADRBK2 | OR3A3 | ENSP00000317578 | ENSP00000291231 | Beta-adrenergic receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | Olfactory receptor 3A3; Odorant receptor; Olfactory receptors, family 3 | 0.600 |
ADRBK2 | OR4K17 | ENSP00000317578 | ENSP00000319197 | Beta-adrenergic receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | Olfactory receptor 4K17; Odorant receptor; Olfactory receptors, family 4 | 0.600 |
ADRBK2 | SEZ6L | ENSP00000317578 | ENSP00000248933 | Beta-adrenergic receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons; Sushi domain containing | 0.902 |
MYL6 | MYL6B | ENSP00000446955 | ENSP00000450385 | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.937 |
MYL6 | MYO18B | ENSP00000446955 | ENSP00000334563 | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.805 |
MYL6 | MYO1C | ENSP00000446955 | ENSP00000352834 | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell’s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | 0.810 |
MYL6 | MYO1F | ENSP00000446955 | ENSP00000344871 | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-If; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity); Myosins, class I | 0.796 |
MYL6 | MYO6 | ENSP00000446955 | ENSP00000358994 | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-VI; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated [...] | 0.793 |
MYL6 | MYO9A | ENSP00000446955 | ENSP00000348349 | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-IXa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.780 |
MYL6B | MYL6 | ENSP00000450385 | ENSP00000446955 | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.937 |
MYL6B | MYO18B | ENSP00000450385 | ENSP00000334563 | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.805 |
MYL6B | MYO1C | ENSP00000450385 | ENSP00000352834 | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell’s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | 0.816 |
MYL6B | MYO1F | ENSP00000450385 | ENSP00000344871 | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-If; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity); Myosins, class I | 0.804 |
MYL6B | MYO6 | ENSP00000450385 | ENSP00000358994 | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-VI; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated [...] | 0.786 |
MYL6B | MYO9A | ENSP00000450385 | ENSP00000348349 | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Unconventional myosin-IXa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.809 |
MYO18B | ADRBK2 | ENSP00000334563 | ENSP00000317578 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Beta-adrenergic receptor kinase 2; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors | 0.901 |
MYO18B | MYL6 | ENSP00000334563 | ENSP00000446955 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.805 |
MYO18B | MYL6B | ENSP00000334563 | ENSP00000450385 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain 6B; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.805 |
MYO18B | MYO1C | ENSP00000334563 | ENSP00000352834 | Unconventional myosin-XVIIIb; May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell’s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | 0.914 |