• Version:
  • 11.0 [archived version]
STRINGSTRING
DEFB104B DEFB104B DEFB106A DEFB106A DEFB106B DEFB106B DEFB107A DEFB107A DEFB107B DEFB107B DEFB105B DEFB105B DEFB103A DEFB103A DEFB104A DEFB104A DEFB105A DEFB105A DEFB108B DEFB108B DEFB103B DEFB103B
"DEFB106B" - Defensin, beta 106B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB106BDefensin, beta 106B; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2; Belongs to the beta-defensin family (65 aa)    
Predicted Functional Partners:
DEFB105B
Beta-defensin 105; Has antibacterial activity; Defensins, beta (78 aa)
     
   
  0.902
DEFB107B
Beta-defensin 107; Has antibacterial activity; Defensins, beta (70 aa)
     
   
  0.879
DEFB105A
Defensin, beta 105A; Has antibacterial activity; Defensins, beta (78 aa)
     
   
  0.874
DEFB107A
Defensin, beta 107A; Has antibacterial activity; Defensins, beta (70 aa)
     
   
  0.850
DEFB106A
Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2; Belongs to the beta-defensin family (65 aa)
     
   
0.829
DEFB104B
Beta-defensin 104; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Belongs to the beta-defensin family (72 aa)
     
   
  0.825
DEFB104A
Defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Defensins, beta (72 aa)
     
   
  0.815
DEFB108B
Beta-defensin 108B; Has antibacterial activity; Defensins, beta (73 aa)
     
   
  0.774
DEFB103B
Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed; Defensins, beta (67 aa)
           
  0.756
DEFB103A
Defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed; Defensins, beta (67 aa)
           
  0.754
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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