node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTL7A | CAPZA3 | ENSP00000334300 | ENSP00000326238 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 0.680 |
ACTL7A | CCIN | ENSP00000334300 | ENSP00000334996 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | 0.619 |
ACTL7A | CGB2 | ENSP00000334300 | ENSP00000352295 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Chorionic gonadotropin beta subunit 2 | 0.589 |
ACTL7A | CTNNAL1 | ENSP00000334300 | ENSP00000320434 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | 0.796 |
ACTL7A | ENAH | ENSP00000334300 | ENSP00000355809 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Protein enabled homolog; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity); ENAH/VASPs | 0.872 |
ACTL7A | HDGFL1 | ENSP00000334300 | ENSP00000442129 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Hepatoma-derived growth factor-like protein 1; Heparin binding growth factor family; Belongs to the HDGF family | 0.680 |
ACTL7A | IKBKAP | ENSP00000334300 | ENSP00000363779 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Elongator complex protein 1; May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK); Belongs to the ELP1/IKA1 family | 0.717 |
ACTL7A | MMEL1 | ENSP00000334300 | ENSP00000367668 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Membrane metallo-endopeptidase-like 1; Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity); Belongs to the peptidase M13 family | 0.603 |
ACTL7A | TES | ENSP00000334300 | ENSP00000350937 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Testin; Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth; LIM domain containing | 0.961 |
ACTL7A | UBQLNL | ENSP00000334300 | ENSP00000369531 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | Ubiquilin-like protein; Ubiquilin family | 0.727 |
CAPZA3 | ACTL7A | ENSP00000326238 | ENSP00000334300 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | 0.680 |
CAPZA3 | CCIN | ENSP00000326238 | ENSP00000334996 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | 0.597 |
CAPZA3 | UBQLNL | ENSP00000326238 | ENSP00000369531 | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | Ubiquilin-like protein; Ubiquilin family | 0.637 |
CCIN | ACTL7A | ENSP00000334996 | ENSP00000334300 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | 0.619 |
CCIN | CAPZA3 | ENSP00000334996 | ENSP00000326238 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) | 0.597 |
CCIN | HDGFL1 | ENSP00000334996 | ENSP00000442129 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | Hepatoma-derived growth factor-like protein 1; Heparin binding growth factor family; Belongs to the HDGF family | 0.573 |
CCIN | UBQLNL | ENSP00000334996 | ENSP00000369531 | Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing | Ubiquilin-like protein; Ubiquilin family | 0.600 |
CGB2 | ACTL7A | ENSP00000352295 | ENSP00000334300 | Chorionic gonadotropin beta subunit 2 | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | 0.589 |
CTNNAL1 | ACTL7A | ENSP00000320434 | ENSP00000334300 | Alpha-catulin; May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | 0.796 |
ENAH | ACTL7A | ENSP00000355809 | ENSP00000334300 | Protein enabled homolog; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity); ENAH/VASPs | Actin-like protein 7A; Actin related proteins; Belongs to the actin family | 0.872 |