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  • 11.0 [archived version]
STRINGSTRING
ZBED1 ZBED1 PLCXD1 PLCXD1 GTPBP6 GTPBP6 N4BP2L1 N4BP2L1 ASMTL ASMTL DHRSX DHRSX HEATR4 HEATR4 SPRY3 SPRY3 PCDH11X PCDH11X FADS3 FADS3 ERMARD ERMARD
"DHRSX" - Dehydrogenase/reductase SDR family member on chromosome X in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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DHRSXDehydrogenase/reductase SDR family member on chromosome X; Involved in the positive regulation of starvation- induced autophagy; Belongs to the short-chain dehydrogenases/reductases (SDR) family (330 aa)    
Predicted Functional Partners:
ZBED1
Zinc finger BED domain-containing protein 1; Binds to 5’-TGTCG[CT]GA[CT]A-3’ DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity (694 aa)
 
   
 
  0.781
GTPBP6
Putative GTP-binding protein 6; Pseudoautosomal region 1 (516 aa)
   
 
  0.696
PLCXD1
PI-PLC X domain-containing protein 1; Phosphatidylinositol specific phospholipase C X domain containing 1; Pseudoautosomal region 1 (323 aa)
           
  0.649
ASMTL
N-acetylserotonin O-methyltransferase-like protein; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity; In the N-terminal section; belongs to the maf family (621 aa)
         
  0.616
SPRY3
Protein sprouty homolog 3; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis; Pseudoautosomal region 2 (288 aa)
           
  0.568
FADS3
Fatty acid desaturase 3 (445 aa)
       
 
  0.536
HEATR4
HEAT repeat-containing protein 4; Armadillo-like helical domain containing (1026 aa)
           
  0.531
PCDH11X
Protocadherin-11 X-linked; Potential calcium-dependent cell-adhesion protein; Non-clustered protocadherins (1347 aa)
           
  0.525
N4BP2L1
NEDD4 binding protein 2 like 1 (243 aa)
           
  0.523
ERMARD
Endoplasmic reticulum membrane-associated RNA degradation protein; May play a role in neuronal migration during embryonic development (678 aa)
           
  0.521
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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