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STRINGSTRING
SYNGR4 SYNGR4 CMTM1 CMTM1 CMTM5 CMTM5 PANK4 PANK4 CMTM3 CMTM3 CKLF CKLF CMTM4 CMTM4 CMTM2 CMTM2 SYNGR1 SYNGR1 SYNGR2 SYNGR2 SYNGR3 SYNGR3
"CMTM4" - CKLF like MARVEL transmembrane domain containing 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
CMTM4CKLF like MARVEL transmembrane domain containing 4 (234 aa)    
Predicted Functional Partners:
CKLF
Chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 (152 aa)
            
  0.906
CMTM3
CKLF like MARVEL transmembrane domain containing 3; Belongs to the chemokine-like factor family (182 aa)
            
  0.905
CMTM1
CKLF like MARVEL transmembrane domain containing 1 (286 aa)
            
  0.905
CMTM2
CKLF like MARVEL transmembrane domain containing 2; Belongs to the chemokine-like factor family (248 aa)
            
  0.905
CMTM5
CKLF like MARVEL transmembrane domain containing 5; Belongs to the chemokine-like factor family (223 aa)
            
  0.716
PANK4
Pantothenate kinase 4; Plays a role in the physiological regulation of the intracellular CoA concentration (773 aa)
            
  0.655
SYNGR2
Synaptogyrin-2; May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane; Belongs to the synaptogyrin family (224 aa)
            
  0.633
SYNGR4
Synaptogyrin-4; Synaptogyrin 4; Synaptogyrins (234 aa)
            
  0.626
SYNGR3
Synaptogyrin-3; May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal; Belongs to the synaptogyrin family (229 aa)
      
   
  0.621
SYNGR1
Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short-term and long-term synaptic plasticity (By similarity); Belongs to the synaptogyrin family (233 aa)
            
  0.615
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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