| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD53 | EVI2A | ENSP00000271324 | ENSP00000247270 | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | 0.515 |
| CD53 | EVI2B | ENSP00000271324 | ENSP00000333779 | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | 0.830 |
| CD53 | HCLS1 | ENSP00000271324 | ENSP00000320176 | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression | 0.769 |
| CD53 | LAPTM5 | ENSP00000271324 | ENSP00000294507 | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family | 0.910 |
| CD53 | LCP2 | ENSP00000271324 | ENSP00000046794 | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | Lymphocyte cytosolic protein 2; Involved in T-cell antigen receptor mediated signaling; SH2 domain containing | 0.757 |
| CD53 | PTPRC | ENSP00000271324 | ENSP00000411355 | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity); Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily | 0.822 |
| EVI2A | CD53 | ENSP00000247270 | ENSP00000271324 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | 0.515 |
| EVI2A | EVI2B | ENSP00000247270 | ENSP00000333779 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | 0.978 |
| EVI2A | LAPTM5 | ENSP00000247270 | ENSP00000294507 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family | 0.449 |
| EVI2A | NF1 | ENSP00000247270 | ENSP00000351015 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | Neurofibromin; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity; Armadillo-like helical domain containing | 0.640 |
| EVI2A | OMG | ENSP00000247270 | ENSP00000247271 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system | 0.820 |
| EVI2A | RNF135 | ENSP00000247270 | ENSP00000328340 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | E3 ubiquitin-protein ligase RNF135; Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production; Ring finger proteins | 0.666 |
| EVI2A | SSH2 | ENSP00000247270 | ENSP00000444743 | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | Protein phosphatase Slingshot homolog 2; Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein; Slingshot protein phosphatases | 0.621 |
| EVI2B | CD53 | ENSP00000333779 | ENSP00000271324 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Leukocyte surface antigen CD53; Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity); CD molecules | 0.830 |
| EVI2B | EVI2A | ENSP00000333779 | ENSP00000247270 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Protein EVI2A; May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor | 0.978 |
| EVI2B | HCLS1 | ENSP00000333779 | ENSP00000320176 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression | 0.679 |
| EVI2B | LAPTM5 | ENSP00000333779 | ENSP00000294507 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells; Belongs to the LAPTM4/LAPTM5 transporter family | 0.777 |
| EVI2B | LCP2 | ENSP00000333779 | ENSP00000046794 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Lymphocyte cytosolic protein 2; Involved in T-cell antigen receptor mediated signaling; SH2 domain containing | 0.689 |
| EVI2B | NF1 | ENSP00000333779 | ENSP00000351015 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Neurofibromin; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity; Armadillo-like helical domain containing | 0.644 |
| EVI2B | OMG | ENSP00000333779 | ENSP00000247271 | Protein EVI2B; Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells; CD molecules | Oligodendrocyte-myelin glycoprotein; Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system | 0.805 |
