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STRINGSTRING
IL20RA IL20RA RAB27A RAB27A OLIG3 OLIG3 IL22RA2 IL22RA2 GPCPD1 GPCPD1 SLC35D3 SLC35D3 SLC35A4 SLC35A4 SLC35B3 SLC35B3 SLC35A5 SLC35A5 SLC35A3 SLC35A3 SLC35C2 SLC35C2
"SLC35D3" - Solute carrier family 35 member D3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SLC35D3Solute carrier family 35 member D3; May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules; Solute carriers (416 aa)    
Predicted Functional Partners:
RAB27A
Ras-related protein Rab-27A; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse; RAB, member RAS oncogene GTPases (221 aa)
            
  0.756
GPCPD1
Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity; Belongs to the glycerophosphoryl diester phosphodiesterase family (672 aa)
        
      0.692
SLC35A5
Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 (424 aa)
      
   
  0.649
SLC35C2
Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers (394 aa)
      
   
  0.645
IL22RA2
Interleukin-22 receptor subunit alpha-2; Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses; Interleukin receptors (263 aa)
            
  0.640
SLC35A3
UDP-N-acetylglucosamine transporter; Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily (367 aa)
      
   
  0.629
SLC35B3
Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers (401 aa)
            
  0.620
OLIG3
Oligodendrocyte transcription factor 3; May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons; Basic helix-loop-helix proteins (272 aa)
            
  0.609
SLC35A4
Probable UDP-sugar transporter protein SLC35A4; Solute carrier family 35 member A4; Belongs to the nucleotide-sugar transporter family. SLC35A subfamily (324 aa)
      
   
  0.595
IL20RA
Interleukin-20 receptor subunit alpha; The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26; Interleukin receptors (553 aa)
      
   
  0.592
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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