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STRINGSTRING
GPR115 GPR115 ACOT6 ACOT6 CCDC108 CCDC108 SAP30BP SAP30BP FASTKD5 FASTKD5 ZNF530 ZNF530 OR4C46 OR4C46 GPR153 GPR153 FAM3D FAM3D TRIM28 TRIM28 TEKT5 TEKT5
"ZNF530" - Zinc finger protein 530 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF530Zinc finger protein 530; May be involved in transcriptional regulation; Zinc fingers C2H2-type (599 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
      
    0.903
OR4C46
Olfactory receptor 4C46; Odorant receptor; Olfactory receptors, family 4 (309 aa)
            
  0.633
CCDC108
Cilia- and flagella-associated protein 65; May play a role in sperm motility; Belongs to the CFAP65 family (1925 aa)
      
   
  0.572
ACOT6
acyl-CoA thioesterase 6 (207 aa)
      
   
  0.565
FASTKD5
FAST kinase domain-containing protein 5, mitochondrial; Plays an important role in the processing of non- canonical mitochondrial mRNA precursors; FASTK mitochondrial RNA binding family (764 aa)
            
  0.543
GPR115
Adhesion G protein-coupled receptor F4; Orphan receptor (695 aa)
            
  0.543
SAP30BP
SAP30-binding protein; Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes; Belongs to the HCNGP family (308 aa)
            
  0.530
TEKT5
Tektin-5; May be a structural component of the sperm flagellum; Tektins (485 aa)
        
 
  0.527
FAM3D
Protein FAM3D; Family with sequence similarity 3 member D; Belongs to the FAM3 family (224 aa)
            
  0.526
GPR153
Probable G-protein coupled receptor 153; Orphan receptor; G protein-coupled receptors, Class A orphans (609 aa)
            
  0.511
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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