node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EBAG9 | IGDCC3 | ENSP00000337675 | ENSP00000332773 | Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.632 |
EBAG9 | UNC119 | ENSP00000337675 | ENSP00000337040 | Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases | Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid- binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Prob [...] | 0.580 |
GPR125 | IGDCC3 | ENSP00000334952 | ENSP00000332773 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.793 |
IGDCC3 | EBAG9 | ENSP00000332773 | ENSP00000337675 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases | 0.632 |
IGDCC3 | GPR125 | ENSP00000332773 | ENSP00000334952 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | 0.793 |
IGDCC3 | PINX1 | ENSP00000332773 | ENSP00000318966 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | PIN2/TERF1-interacting telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor; Belongs to the PINX1 family | 0.656 |
IGDCC3 | PTPN3 | ENSP00000332773 | ENSP00000363667 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Tyrosine-protein phosphatase non-receptor type 3; May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity; FERM domain containing | 0.651 |
IGDCC3 | RNF207 | ENSP00000332773 | ENSP00000367173 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner; Ring finger proteins | 0.677 |
IGDCC3 | SIDT1 | ENSP00000332773 | ENSP00000264852 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | SID1 transmembrane family member 1; In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded | 0.695 |
IGDCC3 | TRIM67 | ENSP00000332773 | ENSP00000355613 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Tripartite motif-containing protein 67; Fibronectin type III domain containing; Belongs to the TRIM/RBCC family | 0.677 |
IGDCC3 | TRIM9 | ENSP00000332773 | ENSP00000298355 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | E3 ubiquitin-protein ligase TRIM9; E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation; Belongs to the TRIM/RBCC family | 0.677 |
IGDCC3 | UNC119 | ENSP00000332773 | ENSP00000337040 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid- binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Prob [...] | 0.722 |
IGDCC3 | VIM | ENSP00000332773 | ENSP00000446007 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally | 0.654 |
PINX1 | IGDCC3 | ENSP00000318966 | ENSP00000332773 | PIN2/TERF1-interacting telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor; Belongs to the PINX1 family | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.656 |
PTPN3 | IGDCC3 | ENSP00000363667 | ENSP00000332773 | Tyrosine-protein phosphatase non-receptor type 3; May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity; FERM domain containing | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.651 |
RNF207 | IGDCC3 | ENSP00000367173 | ENSP00000332773 | RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner; Ring finger proteins | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.677 |
SIDT1 | IGDCC3 | ENSP00000264852 | ENSP00000332773 | SID1 transmembrane family member 1; In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.695 |
SIDT1 | UNC119 | ENSP00000264852 | ENSP00000337040 | SID1 transmembrane family member 1; In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded | Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid- binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Prob [...] | 0.713 |
TRIM67 | IGDCC3 | ENSP00000355613 | ENSP00000332773 | Tripartite motif-containing protein 67; Fibronectin type III domain containing; Belongs to the TRIM/RBCC family | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.677 |
TRIM9 | IGDCC3 | ENSP00000298355 | ENSP00000332773 | E3 ubiquitin-protein ligase TRIM9; E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation; Belongs to the TRIM/RBCC family | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.677 |