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  • 11.0 [archived version]
STRINGSTRING
BCL6B BCL6B SULT1A1 SULT1A1 SULT1A3 SULT1A3 PDZRN4 PDZRN4 MPPED1 MPPED1 SULT4A1 SULT4A1 ERMN ERMN GABRA6 GABRA6 NDRG4 NDRG4 LZTS1 LZTS1 SLC35B2 SLC35B2
"SULT4A1" - Sulfotransferase 4A1 in Homo sapiens
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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SULT4A1Sulfotransferase 4A1; Atypical sulfotransferase family member with very low affinity for 3’-phospho-5’-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS; Sulfotransferases, cytosolic (284 aa)    
Predicted Functional Partners:
SLC35B2
Adenosine 3’-phospho 5’-phosphosulfate transporter 1; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF- kappa-B and MAPK pathways; Solute carriers (432 aa)
     
   
  0.932
SULT1A1
Sulfotransferase 1A1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N- hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk; Sulfotransferases, cytosolic (295 aa)
   
 
 
0.848
SULT1A3
Sulfotransferase 1A3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs (295 aa)
   
 
 
0.845
MPPED1
Metallophosphoesterase domain-containing protein 1; May have metallophosphoesterase activity (in vitro) (326 aa)
     
   
  0.792
NDRG4
Protein NDRG4; Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner (391 aa)
     
   
  0.755
PDZRN4
PDZ domain containing ring finger 4 (1036 aa)
     
   
  0.726
ERMN
Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) (297 aa)
     
      0.722
GABRA6
Gamma-aminobutyric acid receptor subunit alpha-6; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits (453 aa)
     
   
  0.714
LZTS1
Leucine zipper putative tumor suppressor 1; Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor; Leucine zipper tumor suppressor family (596 aa)
     
   
  0.691
BCL6B
B-cell CLL/lymphoma 6 member B protein; Acts as a sequence-specific transcriptional repressor in association with BCL6. May function in a narrow stage or be related to some events in the early B-cell development; BTB domain containing (479 aa)
       
      0.689
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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