OTOP2 protein (human) - STRING database

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Score

OTOP2

Otopetrin-2; Otopetrin 2 (562 aa)

Predicted Functional Partners:

HID1

0.819

CDR2L

0.792

TMEM128

0.743

USH1G

0.686

TMIGD1

0.657

OR1D5

0.630

FADS6

0.626

GUCA2B

0.618

MS4A12

0.601

CTCF

0.581

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDR2L	FADS6	ENSP00000336587	ENSP00000481684	Cerebellar degeneration related protein 2 like	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.626
CDR2L	HID1	ENSP00000336587	ENSP00000413520	Cerebellar degeneration related protein 2 like	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	0.709
CDR2L	OR1D5	ENSP00000336587	ENSP00000459028	Cerebellar degeneration related protein 2 like	Olfactory receptor 1D5; Odorant receptor; Olfactory receptors, family 1	0.517
CDR2L	OTOP2	ENSP00000336587	ENSP00000332528	Cerebellar degeneration related protein 2 like	Otopetrin-2; Otopetrin 2	0.792
CDR2L	TMEM128	ENSP00000336587	ENSP00000372201	Cerebellar degeneration related protein 2 like	Transmembrane protein 128	0.736
CTCF	OTOP2	ENSP00000264010	ENSP00000332528	Transcriptional repressor CTCF; Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by ac [...]	Otopetrin-2; Otopetrin 2	0.581
FADS6	CDR2L	ENSP00000481684	ENSP00000336587	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Cerebellar degeneration related protein 2 like	0.626
FADS6	HID1	ENSP00000481684	ENSP00000413520	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	0.626
FADS6	OTOP2	ENSP00000481684	ENSP00000332528	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Otopetrin-2; Otopetrin 2	0.626
FADS6	TMEM128	ENSP00000481684	ENSP00000372201	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Transmembrane protein 128	0.626
FADS6	USH1G	ENSP00000481684	ENSP00000480279	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	Usher syndrome type-1G protein; Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing; Ankyrin repeat domain containing	0.797
GUCA2B	MS4A12	ENSP00000361662	ENSP00000016913	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	Membrane-spanning 4-domains subfamily A member 12; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family	0.603
GUCA2B	OTOP2	ENSP00000361662	ENSP00000332528	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	Otopetrin-2; Otopetrin 2	0.618
GUCA2B	TMIGD1	ENSP00000361662	ENSP00000332404	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	Transmembrane and immunoglobulin domain-containing protein 1; May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival; I-set domain containing	0.728
HID1	CDR2L	ENSP00000413520	ENSP00000336587	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	Cerebellar degeneration related protein 2 like	0.709
HID1	FADS6	ENSP00000413520	ENSP00000481684	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family	0.626
HID1	OTOP2	ENSP00000413520	ENSP00000332528	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	Otopetrin-2; Otopetrin 2	0.819
HID1	TMEM128	ENSP00000413520	ENSP00000372201	Protein HID1; May play an important role in the development of cancers in a broad range of tissues	Transmembrane protein 128	0.774
MS4A12	GUCA2B	ENSP00000016913	ENSP00000361662	Membrane-spanning 4-domains subfamily A member 12; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family	Guanylate cyclase activator 2B; Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport	0.603
MS4A12	OTOP2	ENSP00000016913	ENSP00000332528	Membrane-spanning 4-domains subfamily A member 12; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family	Otopetrin-2; Otopetrin 2	0.601

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