• Version:
  • 11.0 [archived version]
STRINGSTRING
TRIM36 TRIM36 ZNF558 ZNF558 RFPL4A RFPL4A TKTL2 TKTL2 TRIM61 TRIM61 TRIM56 TRIM56 BSPRY BSPRY UMODL1 UMODL1
"TRIM61" - Putative tripartite motif-containing protein 61 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TRIM61Putative tripartite motif-containing protein 61; Tripartite motif containing 61; Ring finger proteins (209 aa)    
Predicted Functional Partners:
ZNF558
Zinc finger protein 558; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (402 aa)
     
 
  0.605
RFPL4A
Ret finger protein like 4A; Ring finger proteins (287 aa)
     
   
  0.541
BSPRY
B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity (402 aa)
           
  0.450
TRIM36
E3 ubiquitin-protein ligase TRIM36; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization; Belongs to the TRIM/RBCC family (728 aa)
           
  0.442
UMODL1
Uromodulin like 1 (1446 aa)
     
   
  0.431
TKTL2
Transketolase-like protein 2; Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis; Belongs to the transketolase family (626 aa)
     
   
  0.429
TRIM56
E3 ubiquitin-protein ligase TRIM56; E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity. In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets TMEM173/STING to ’Lys-63’-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta (By similarity). Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling. Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXC [...] (755 aa)
           
  0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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