PRAMEF1 protein (human) - STRING database

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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some 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

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Score

PRAMEF1

PRAME family member 1; Belongs to the PRAME family (474 aa)

Predicted Functional Partners:

ZSCAN4

0.651

LOC649330

0.648

TRIM43

0.571

HNRNPCP5

0.563

OR5H6

0.540

MBD3L2

0.524

KHDC1L

0.517

DUX4

0.515

DUXA

0.499

DUX4L8

0.476

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUX4	DUX4L8	ENSP00000458065	ENSP00000485452	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	0.801
DUX4	KHDC1L	ENSP00000458065	ENSP00000359415	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.511
DUX4	MBD3L2	ENSP00000458065	ENSP00000370800	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	methyl-CpG binding domain protein 3 like 2; Belongs to the MBD3L family	0.560
DUX4	PRAMEF1	ENSP00000458065	ENSP00000332134	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	PRAME family member 1; Belongs to the PRAME family	0.515
DUX4	TRIM43	ENSP00000458065	ENSP00000272395	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Tripartite motif containing 43; Ring finger proteins	0.674
DUX4	ZSCAN4	ENSP00000458065	ENSP00000321963	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity); SCAN domain containing	0.797
DUX4L8	DUX4	ENSP00000485452	ENSP00000458065	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	0.801
DUX4L8	KHDC1L	ENSP00000485452	ENSP00000359415	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.520
DUX4L8	MBD3L2	ENSP00000485452	ENSP00000370800	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	methyl-CpG binding domain protein 3 like 2; Belongs to the MBD3L family	0.556
DUX4L8	PRAMEF1	ENSP00000485452	ENSP00000332134	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	PRAME family member 1; Belongs to the PRAME family	0.476
DUX4L8	TRIM43	ENSP00000485452	ENSP00000272395	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	Tripartite motif containing 43; Ring finger proteins	0.639
DUX4L8	ZSCAN4	ENSP00000485452	ENSP00000321963	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity); SCAN domain containing	0.796
DUXA	HNRNPCP5	ENSP00000452398	ENSP00000479203	Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes	Heterogeneous nuclear ribonucleoprotein C-like 2; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs	0.533
DUXA	KHDC1L	ENSP00000452398	ENSP00000359415	Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.473
DUXA	LOC649330	ENSP00000452398	ENSP00000478017	Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes	Heterogeneous nuclear ribonucleoprotein C-like	0.587
DUXA	PRAMEF1	ENSP00000452398	ENSP00000332134	Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes	PRAME family member 1; Belongs to the PRAME family	0.499
DUXA	ZSCAN4	ENSP00000452398	ENSP00000321963	Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes	Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity); SCAN domain containing	0.577
HNRNPCP5	DUXA	ENSP00000479203	ENSP00000452398	Heterogeneous nuclear ribonucleoprotein C-like 2; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs	Double homeobox protein A; Putative transcription factor; PRD class homeoboxes and pseudogenes	0.533
HNRNPCP5	KHDC1L	ENSP00000479203	ENSP00000359415	Heterogeneous nuclear ribonucleoprotein C-like 2; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.648
HNRNPCP5	PRAMEF1	ENSP00000479203	ENSP00000332134	Heterogeneous nuclear ribonucleoprotein C-like 2; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs	PRAME family member 1; Belongs to the PRAME family	0.563

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