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  • 11.0 [archived version]
STRINGSTRING
CPNE8 CPNE8 LRRC39 LRRC39 C1orf158 C1orf158 ACTRT1 ACTRT1 FRYL FRYL NKAIN2 NKAIN2 WSCD2 WSCD2 RNF167 RNF167 CTNNBL1 CTNNBL1 VSTM2B VSTM2B LRP2BP LRP2BP
"WSCD2" - WSC domain containing 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
WSCD2WSC domain containing 2; Belongs to the WSCD family (565 aa)    
Predicted Functional Partners:
C1orf158
Uncharacterized protein C1orf158; Chromosome 1 open reading frame 158 (194 aa)
            
  0.710
NKAIN2
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2; Sodium/potassium transporting ATPase interacting 2 (208 aa)
      
   
  0.604
LRP2BP
LRP2-binding protein; May act as an adapter that regulates LRP2 function (347 aa)
        
 
  0.596
LRRC39
Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart (339 aa)
            
  0.585
RNF167
E3 ubiquitin-protein ligase RNF167; May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition; Ring finger proteins (350 aa)
            
  0.580
ACTRT1
Actin related protein T1 (376 aa)
            
  0.575
FRYL
Protein furry homolog-like; Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator; Belongs to the furry protein family (3013 aa)
            
  0.575
VSTM2B
V-set and transmembrane domain containing 2B (285 aa)
      
   
  0.562
CPNE8
Copine-8; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes; Copines (564 aa)
      
   
  0.521
CTNNBL1
Beta-catenin-like protein 1; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis; Armadillo-like helical domain containing (563 aa)
            
  0.519
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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