• Version:
  • 11.0 [archived version]
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LSM12 LSM12 DNAH17 DNAH17 HSPE1-MOB4 HSPE1-MOB4 MOB4 MOB4 SSR2 SSR2 INTS12 INTS12 C16orf72 C16orf72 METTL22 METTL22 NEURL1 NEURL1 CARHSP1 CARHSP1 TMEM186 TMEM186
"C16orf72" - UPF0472 protein C16orf72 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
C16orf72UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 (275 aa)    
Predicted Functional Partners:
TMEM186
Transmembrane protein 186 (213 aa)
           
  0.705
DNAH17
Dynein heavy chain 17, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Belongs to the dynein heavy chain family (4462 aa)
           
  0.626
METTL22
Methyltransferase-like protein 22; Protein N-lysine methyltransferase. In vitro methylates KIN; Belongs to the methyltransferase superfamily. METTL22 family (404 aa)
           
  0.590
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins; Belongs to the TRAP-beta family (183 aa)
           
  0.580
INTS12
Integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (462 aa)
       
 
  0.546
CARHSP1
Calcium-regulated heat-stable protein 1; Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro) (147 aa)
           
  0.530
NEURL1
E3 ubiquitin-protein ligase NEURL1; Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element- binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor; [...] (574 aa)
           
  0.514
HSPE1-MOB4
HSPE1-MOB4 readthrough; Belongs to the GroES chaperonin family (261 aa)
           
  0.505
MOB4
MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family (225 aa)
           
  0.505
LSM12
LSM12 homolog (195 aa)
           
  0.497
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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