node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C16orf72 | CARHSP1 | ENSP00000331720 | ENSP00000379838 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | Calcium-regulated heat-stable protein 1; Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro) | 0.530 |
C16orf72 | DNAH17 | ENSP00000331720 | ENSP00000374490 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | Dynein heavy chain 17, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Belongs to the dynein heavy chain family | 0.626 |
C16orf72 | HSPE1-MOB4 | ENSP00000331720 | ENSP00000474534 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | HSPE1-MOB4 readthrough; Belongs to the GroES chaperonin family | 0.505 |
C16orf72 | INTS12 | ENSP00000331720 | ENSP00000415433 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | Integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | 0.546 |
C16orf72 | LSM12 | ENSP00000331720 | ENSP00000466718 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | LSM12 homolog | 0.497 |
C16orf72 | METTL22 | ENSP00000331720 | ENSP00000371345 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | Methyltransferase-like protein 22; Protein N-lysine methyltransferase. In vitro methylates KIN; Belongs to the methyltransferase superfamily. METTL22 family | 0.590 |
C16orf72 | MOB4 | ENSP00000331720 | ENSP00000315702 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family | 0.505 |
C16orf72 | NEURL1 | ENSP00000331720 | ENSP00000358795 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | E3 ubiquitin-protein ligase NEURL1; Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element- binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor; [...] | 0.514 |
C16orf72 | SSR2 | ENSP00000331720 | ENSP00000295702 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins; Belongs to the TRAP-beta family | 0.580 |
C16orf72 | TMEM186 | ENSP00000331720 | ENSP00000331640 | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | Transmembrane protein 186 | 0.705 |
CARHSP1 | C16orf72 | ENSP00000379838 | ENSP00000331720 | Calcium-regulated heat-stable protein 1; Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro) | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | 0.530 |
CARHSP1 | METTL22 | ENSP00000379838 | ENSP00000371345 | Calcium-regulated heat-stable protein 1; Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro) | Methyltransferase-like protein 22; Protein N-lysine methyltransferase. In vitro methylates KIN; Belongs to the methyltransferase superfamily. METTL22 family | 0.473 |
CARHSP1 | TMEM186 | ENSP00000379838 | ENSP00000331640 | Calcium-regulated heat-stable protein 1; Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro) | Transmembrane protein 186 | 0.587 |
DNAH17 | C16orf72 | ENSP00000374490 | ENSP00000331720 | Dynein heavy chain 17, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Belongs to the dynein heavy chain family | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | 0.626 |
HSPE1-MOB4 | C16orf72 | ENSP00000474534 | ENSP00000331720 | HSPE1-MOB4 readthrough; Belongs to the GroES chaperonin family | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | 0.505 |
HSPE1-MOB4 | LSM12 | ENSP00000474534 | ENSP00000466718 | HSPE1-MOB4 readthrough; Belongs to the GroES chaperonin family | LSM12 homolog | 0.497 |
HSPE1-MOB4 | SSR2 | ENSP00000474534 | ENSP00000295702 | HSPE1-MOB4 readthrough; Belongs to the GroES chaperonin family | Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins; Belongs to the TRAP-beta family | 0.418 |
INTS12 | C16orf72 | ENSP00000415433 | ENSP00000331720 | Integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | 0.546 |
LSM12 | C16orf72 | ENSP00000466718 | ENSP00000331720 | LSM12 homolog | UPF0472 protein C16orf72; Chromosome 16 open reading frame 72 | 0.497 |
LSM12 | HSPE1-MOB4 | ENSP00000466718 | ENSP00000474534 | LSM12 homolog | HSPE1-MOB4 readthrough; Belongs to the GroES chaperonin family | 0.497 |