• Version:
  • 11.0 [archived version]
STRINGSTRING
KNDC1 KNDC1 PCP4L1 PCP4L1 DNAJC9 DNAJC9 CCDC38 CCDC38 SPOCD1 SPOCD1 ZKSCAN2 ZKSCAN2 ARMC2 ARMC2 TSPYL5 TSPYL5 SH3TC1 SH3TC1 SH3BP5L SH3BP5L FBXL13 FBXL13
"ZKSCAN2" - Zinc finger protein with KRAB and SCAN domains 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZKSCAN2Zinc finger protein with KRAB and SCAN domains 2; May be involved in transcriptional regulation; Myb/SANT domain containing (967 aa)    
Predicted Functional Partners:
SPOCD1
Protein phosphatase 1 regulatory subunits (1216 aa)
           
  0.606
DNAJC9
DnaJ homolog subfamily C member 9; May play a role as co-chaperone of the Hsp70 family proteins HSPA1A, HSPA1B and HSPA8; DNAJ heat shock proteins (260 aa)
       
 
  0.584
SH3BP5L
SH3 binding domain protein 5 like (393 aa)
           
  0.522
CCDC38
Coiled-coil domain containing 38 (563 aa)
       
 
  0.495
SH3TC1
SH3 domain and tetratricopeptide repeats 1 (1336 aa)
           
  0.493
TSPYL5
Testis-specific Y-encoded-like protein 5; Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7 (417 aa)
     
 
  0.478
FBXL13
F-box/LRR-repeat protein 13; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; Cilia and flagella associated (735 aa)
     
 
  0.467
PCP4L1
Purkinje cell protein 4 like 1; Belongs to the PCP4 family (68 aa)
           
  0.462
KNDC1
Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence (1749 aa)
     
   
  0.462
ARMC2
Armadillo repeat containing 2 (867 aa)
       
 
  0.453
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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