GPR173 protein (human) - STRING database

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Score

GPR173

Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans (373 aa)

Predicted Functional Partners:

SMIM20

0.669

GPR144

0.596

TMEM87B

0.579

GPR174

0.575

EFHC1

0.566

GPR176

0.538

THOP1

0.516

GPR157

0.511

GPR20

0.477

TSPYL2

0.463

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFHC1	GPR173	ENSP00000360107	ENSP00000331600	EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death; EF-hand domain containing	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	0.566
GPR144	GPR157	ENSP00000335156	ENSP00000366628	Adhesion G-protein coupled receptor D2; Orphan receptor	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.649
GPR144	GPR173	ENSP00000335156	ENSP00000331600	Adhesion G-protein coupled receptor D2; Orphan receptor	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	0.596
GPR144	GPR174	ENSP00000335156	ENSP00000276077	Adhesion G-protein coupled receptor D2; Orphan receptor	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	0.687
GPR144	GPR176	ENSP00000335156	ENSP00000453076	Adhesion G-protein coupled receptor D2; Orphan receptor	G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production	0.596
GPR157	GPR144	ENSP00000366628	ENSP00000335156	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Adhesion G-protein coupled receptor D2; Orphan receptor	0.649
GPR157	GPR173	ENSP00000366628	ENSP00000331600	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	0.511
GPR157	GPR174	ENSP00000366628	ENSP00000276077	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	0.595
GPR173	EFHC1	ENSP00000331600	ENSP00000360107	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death; EF-hand domain containing	0.566
GPR173	GPR144	ENSP00000331600	ENSP00000335156	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Adhesion G-protein coupled receptor D2; Orphan receptor	0.596
GPR173	GPR157	ENSP00000331600	ENSP00000366628	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.511
GPR173	GPR174	ENSP00000331600	ENSP00000276077	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	0.575
GPR173	GPR176	ENSP00000331600	ENSP00000453076	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production	0.538
GPR173	GPR20	ENSP00000331600	ENSP00000366970	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP; G protein-coupled receptors, Class A orphans	0.477
GPR173	SMIM20	ENSP00000331600	ENSP00000427407	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Small integral membrane protein 20; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Promotes the progression of complex assembly after the association of MT- CO1/COX1 with COX4I1 and COX6C. Chaperone-like assembly factor required to stabilize newly synthesized MT-CO1/COX1 and to prevent its premature turnover	0.669
GPR173	THOP1	ENSP00000331600	ENSP00000304467	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Thimet oligopeptidase; Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments; M3 metallopeptidases	0.516
GPR173	TMEM87B	ENSP00000331600	ENSP00000283206	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Transmembrane protein 87B; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN); Belongs to the LU7TM family. TMEM87 subfamily	0.579
GPR173	TSPYL2	ENSP00000331600	ENSP00000364591	Probable G-protein coupled receptor 173; Orphan receptor; G protein-coupled receptors, Class A orphans	Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression	0.463
GPR174	GPR144	ENSP00000276077	ENSP00000335156	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	Adhesion G-protein coupled receptor D2; Orphan receptor	0.687
GPR174	GPR157	ENSP00000276077	ENSP00000366628	Probable G-protein coupled receptor 174; Putative receptor for purines coupled to G-proteins; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger; 7TM orphan receptors	0.595

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