• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM126B FAM126B DRAM2 DRAM2 ZNF778 ZNF778 TMEM87A TMEM87A TMEM17 TMEM17 C11orf87 C11orf87 FAN1 FAN1 TCF20 TCF20 CACNB2 CACNB2 TMEM115 TMEM115 DDX10 DDX10
"C11orf87" - Uncharacterized protein C11orf87 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C11orf87Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87 (197 aa)    
Predicted Functional Partners:
TMEM87A
Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) (555 aa)
           
  0.742
TMEM17
Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family (198 aa)
           
  0.710
DRAM2
DNA damage-regulated autophagy modulator protein 2; Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1; Belongs to the DRAM/TMEM150 family (266 aa)
           
  0.653
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting (660 aa)
           
  0.539
TCF20
Transcription factor 20; Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator (1960 aa)
           
  0.509
FAN1
Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL- induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Not involved in DNA double-strand breaks resection. Acts as a 5’-3’ exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Pro [...] (1017 aa)
           
  0.477
TMEM115
Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi; Rhomboid family (351 aa)
           
  0.473
DDX10
Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily (875 aa)
           
  0.426
FAM126B
Protein FAM126B; Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane; Belongs to the FAM126 family (530 aa)
     
   
  0.422
ZNF778
Zinc finger protein 778; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (757 aa)
           
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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