• Version:
  • 11.0 [archived version]
STRINGSTRING
LEKR1 LEKR1 WDR4 WDR4 WBP11 WBP11 HMG20A HMG20A KIAA0825 KIAA0825 RGS8 RGS8 OR4D6 OR4D6 LOC154872 LOC154872 C1orf167 C1orf167 OR5C1 OR5C1 HS6ST3 HS6ST3
"KIAA0825" - Uncharacterized protein KIAA0825 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
KIAA0825Uncharacterized protein KIAA0825; Armadillo-like helical domain containing (324 aa)    
Predicted Functional Partners:
LOC154872
annotation not available (90 aa)
           
  0.837
C1orf167
Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167 (1468 aa)
           
  0.737
OR5C1
Olfactory receptor 5C1; Odorant receptor; Olfactory receptors, family 5 (320 aa)
           
  0.668
LEKR1
Leucine-, glutamate- and lysine-rich protein 1; Leucine, glutamate and lysine rich 1 (132 aa)
           
  0.542
WBP11
WW domain-binding protein 11; Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity; Protein phosphatase 1 regulatory subunits (641 aa)
           
  0.540
RGS8
Regulator of G-protein signaling 8; Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling (By similarity) (198 aa)
           
  0.470
WDR4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit; Belongs to the WD repeat TRM82 family (412 aa)
           
  0.440
HMG20A
High mobility group protein 20A; Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity); Non-canonical high mobility group (347 aa)
           
  0.428
OR4D6
Olfactory receptor 4D6; Odorant receptor; Olfactory receptors, family 4 (314 aa)
           
  0.422
HS6ST3
Heparan-sulfate 6-O-sulfotransferase 3; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3’-phosphoadenosine 5’-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate; Sulfotransferases, membrane bound (471 aa)
           
  0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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