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STRINGSTRING
IQUB IQUB PTPDC1 PTPDC1 FAM81B FAM81B CFAP45 CFAP45 ENKUR ENKUR LRRIQ1 LRRIQ1 TTC18 TTC18 CCDC113 CCDC113 WDR16 WDR16 TRPC1 TRPC1 TRPC5 TRPC5
"ENKUR" - Enkurin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ENKUREnkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel; Cilia and flagella associated (256 aa)    
Predicted Functional Partners:
CFAP45
Cilia and flagella associated protein 45; Belongs to the CFAP45 family (551 aa)
      
 
  0.864
TRPC5
Short transient receptor potential channel 5; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion; Protein phosphatase 1 regulatory subunits (973 aa)
            
  0.754
CCDC113
Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation (377 aa)
      
   
  0.712
TRPC1
Short transient receptor potential channel 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion; Transient receptor potential cation channels (793 aa)
            
  0.711
WDR16
Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival (620 aa)
      
   
  0.653
IQUB
IQ and ubiquitin-like domain-containing protein; May play roles in cilia formation and/or maintenance (791 aa)
      
   
  0.640
FAM81B
Protein FAM81B; Family with sequence similarity 81 member B (452 aa)
      
   
  0.636
LRRIQ1
Leucine rich repeats and IQ motif containing 1 (1722 aa)
      
   
  0.634
PTPDC1
Protein tyrosine phosphatase domain-containing protein 1; May play roles in cilia formation and/or maintenance; CDC14 phosphatases (808 aa)
            
  0.626
TTC18
Cilia- and flagella-associated protein 70; Tetratricopeptide repeat domain 18; Belongs to the CFAP70 family (1121 aa)
      
   
  0.616
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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