• Version:
  • 11.0 [archived version]
STRINGSTRING
CA5B CA5B GTF2A1 GTF2A1 EIF2S3 EIF2S3 ZFX ZFX HDHD1 HDHD1 CXorf38 CXorf38 NFYC NFYC MRPL53 MRPL53 C11orf49 C11orf49 SCAF8 SCAF8 C11orf71 C11orf71
"CXorf38" - Uncharacterized protein CXorf38 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXorf38Uncharacterized protein CXorf38; Chromosome X open reading frame 38 (319 aa)    
Predicted Functional Partners:
NFYC
Nuclear transcription factor Y subunit gamma; Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5’- CCAAT-3’ box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors (354 aa)
       
      0.742
EIF2S3
Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...] (472 aa)
     
   
  0.562
HDHD1
Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family (251 aa)
     
   
  0.525
C11orf49
UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family (337 aa)
           
  0.514
C11orf71
Uncharacterized protein C11orf71; Chromosome 11 open reading frame 71 (147 aa)
           
  0.495
ZFX
Zinc finger X-chromosomal protein; Probable transcriptional activator; Zinc fingers C2H2-type (805 aa)
     
   
  0.450
CA5B
Carbonic anhydrase 5B, mitochondrial; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family (317 aa)
     
   
  0.448
MRPL53
Mitochondrial ribosomal protein L53 (112 aa)
           
  0.448
GTF2A1
Transcription initiation factor IIA subunit 1; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity; Belongs to the TFIIA subunit 1 family (376 aa)
     
   
  0.432
SCAF8
Protein SCAF8; May play a role in mRNA processing; RNA binding motif containing (1349 aa)
     
   
  0.431
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]